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Using Patient-Specific Modeling of the Heart for Risk Stratification of Ventricular Arrhythmia in Patients with Hypertrophic Cardiomyopathy (HCM) via Image-Based Computational Simulations

Unmet NeedHyperthrophic cardiomyopathy (HCM), predominantly an asymptomatic disease, frequently leads to sudden cardiac death resulting from ventricular arrhythmias, i.e. abnormal uncoordinated heart rhythms, particularly among young patients. For patients at high risk for sudden cardiac death, mortality is reduced by the prophylactic insertion of implantable...

Published: 7/4/2024 | Inventor(s): Natalia Trayanova, Mark Cartoski, Patrick Boyle, Adityo Prakosa

Keywords(s): Cardiovascular Diseases, Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Disease Indication, Physics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Computers, Electronics & Software

Using Patient-Specific Modeling of the Heart for Risk Stratification for Ventricular Arrhythmia in Patients with Repaired Tetralogy of Fallot (TOF) via Image-Based Computational Simulations

The JHU inventors previous invention (C11304) provides a non-invasive method to identify the optimal ablation sites for infarct-related ventricular tachycardia (VT) by using 3D electrophysiological heart simulations with a model reconstructed from the patient’s late gadolinium-enhanced (LGE) MRI image. In this application, the inventors extend that...

Published: 7/4/2024 | Inventor(s): Natalia Trayanova, Adityo Prakosa, Mark Cartoski, Patrick Boyle

Keywords(s): Arrhythmias, Cardiovascular Diseases, Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Disease Indication, Physics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Arrhythmias, Technology Classifications > Computers, Electronics & Software, Clinical and Disease Specializations > Cardiovascular