Search Results - adityo+prakosa

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OPtimal Target Identification via Modeling of Arrhythmogenesis

Unmet Need· Atrial fibrillation affects millions of patients worldwide, with the number expected to grow 2.5-fold in the next 40 years. (Boyle et al., 2016) Ablation of cardiac tissue around the pulmonary veins is a standard treatment, but fails 20-40% of the time in patients with a type of atrial fibrillation called persistent atrial fibrillation....

Published: 6/28/2024 | Inventor(s): Natalia Trayanova, Adityo Prakosa, Ryan Bradley, Eugene Kholmovski, Syed Yusuf Ali, Carolyna Yamamoto

Keywords(s):

Category(s): Clinical and Disease Specializations > Cardiovascular > Arrhythmias, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools

Personalized Heart Modeling Using Intramyocardial Fat Deposition on Computed Tomography to Predict Ablation Targets

Unmet NeedVentricular tachycardia (VT) is a life-threatening arrhythmia that contributes significantly to the mortality and morbidity of cardiovascular patients. Catheter ablation of VTs can potentially be curative, but recurrence rates remain unacceptably high. Major technological advancements in VT ablation are often highly invasive, time-consuming,...

Published: 6/28/2024 | Inventor(s): Natalia Trayanova, Eric Sung, Adityo Prakosa, Shijie Zhou

Keywords(s):

Category(s): Clinical and Disease Specializations > Cardiovascular > Ventricular Tachycardia, Technology Classifications > Computers, Electronics & Software

Using Patient-Specific Modeling of the Heart for Prediction of Optimal Targets for Catheter Ablation of Ventricular Tachycardia in Patients with Myocardial Infarction or Fibrosis and ICDs

Unmet NeedVentricular tachycardia (VT) is a heart rhythm disorder that affects hundreds of thousands of Americans every year. VT is defined as an irregular accelerated heart rate due to abnormal electrical signaling in the heart’s lower chambers. Implantable Cardioverter Defibrillators (ICDs) can protect high-risk patients from sudden cardiac arrest...

Published: 6/27/2024 | Inventor(s): Natalia Trayanova, Sohail Zahid, Adityo Prakosa

Keywords(s): Discovery/Research Tools, Heat Intervention, In Vitro Research Tool, Interventional and Surgical Systems, Surgical Intervention Method, Target-based Screening Tool

Category(s): Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools, Technology Classifications > Medical Devices, Technology Classifications > Therapeutic Modalities, Technology Classifications > Diagnostics

Using Patient-Specific Modeling of the Heart for Risk Stratification of Ventricular Arrhythmia in Patients with Hypertrophic Cardiomyopathy (HCM) via Image-Based Computational Simulations

Unmet NeedHyperthrophic cardiomyopathy (HCM), predominantly an asymptomatic disease, frequently leads to sudden cardiac death resulting from ventricular arrhythmias, i.e. abnormal uncoordinated heart rhythms, particularly among young patients. For patients at high risk for sudden cardiac death, mortality is reduced by the prophylactic insertion of implantable...

Published: 6/27/2024 | Inventor(s): Natalia Trayanova, Mark Cartoski, Patrick Boyle, Adityo Prakosa

Keywords(s): Cardiovascular Diseases, Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Disease Indication, Physics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Computers, Electronics & Software

Using Patient-Specific Modeling of the Heart for Risk Stratification for Ventricular Arrhythmia in Patients with Repaired Tetralogy of Fallot (TOF) via Image-Based Computational Simulations

The JHU inventors previous invention (C11304) provides a non-invasive method to identify the optimal ablation sites for infarct-related ventricular tachycardia (VT) by using 3D electrophysiological heart simulations with a model reconstructed from the patient’s late gadolinium-enhanced (LGE) MRI image. In this application, the inventors extend that...

Published: 6/27/2024 | Inventor(s): Natalia Trayanova, Adityo Prakosa, Mark Cartoski, Patrick Boyle

Keywords(s): Arrhythmias, Cardiovascular Diseases, Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Disease Indication, Physics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Arrhythmias, Technology Classifications > Computers, Electronics & Software, Clinical and Disease Specializations > Cardiovascular