Search Results - patrick+boyle

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Simulation Prediction of Optimal Targets for Catheter Ablation of Left Atrial Flutter in Patients with Atrial Structural Remodeling

Unmet NeedLeft atrial flutter (LAFL) is a common atrial arrhythmia that develops in up to 31% of patients who had prior cardiac surgery or atrial fibrillation ablation. LAFL is caused by the presence of a reentrant circuit, which occurs when an electrical impulse continues to propagate and re-excite cardiac tissue, leading to uncoordinated, repeated...

Published: 3/13/2025 | Inventor(s): Natalia Trayanova, Sohail Zahid, Patrick Boyle

Keywords(s): Discovery/Research Tools, In Vitro Research Tool, Target-based Screening Tool

Category(s): Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools, Technology Classifications > Diagnostics

Using Patient-Specific Modeling of the Heart for Risk Stratification for Ventricular Arrhythmia in Patients with Repaired Tetralogy of Fallot (TOF) via Image-Based Computational Simulations

The JHU inventors previous invention (C11304) provides a non-invasive method to identify the optimal ablation sites for infarct-related ventricular tachycardia (VT) by using 3D electrophysiological heart simulations with a model reconstructed from the patient’s late gadolinium-enhanced (LGE) MRI image. In this application, the inventors extend that...

Published: 3/13/2025 | Inventor(s): Natalia Trayanova, Adityo Prakosa, Mark Cartoski, Patrick Boyle

Keywords(s): Arrhythmias, Cardiovascular Diseases, Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Disease Indication, Physics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Arrhythmias, Technology Classifications > Computers, Electronics & Software, Clinical and Disease Specializations > Cardiovascular

Prediction of Targets for Catheter Ablation of Persistent Atrial Fibrillation based on Analysis of Patient-specific Fibrosis Patterns

Novel Technique to Identify Ablation Targets in Atrial Fibrillation Patients With FibrosisJHU REF: C13278Invention novelty: A method to identify a set of potential atrial fibrillation (AF) ablation targets, in real time, by analyzing the personalized spatial distribution of atrial fibrosis.Value Proposition:Catheter-based ablation to terminate atrial...

Published: 3/13/2025 | Inventor(s): Patrick Boyle, Sohail Zahid, Natalia Trayanova

Keywords(s): Atrial Fibrillation, Atrial Fibrillation (AF), Cardiovascular Diseases, Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Disease Indication, Integrated Imaging System, Interventional and Surgical Systems, Physics, Surgical Navigation

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Atrial Fibrillation, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices > Surgical, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Medical Devices