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Lipid Nanoparticle Formulations Capable of Migrating to Systemic Organs Following Intramuscular Administration

Value Proposition:Organ-targeted drug or mRNA delivery to focus therapy on specific tissues. Accessible intramuscular administration, offering broadly applicable, out-of-the-box drug delivery system for a range of therapeutics.Achieves organ-specific delivery without antibodies or targeting ligands, simplifying manufacturing and scalability.Unmet NeedTargeting...

Published: 9/12/2025 | Inventor(s): Hai-Quan Mao, Yining Zhu, Christine Wei, Di Yu

Keywords(s):

Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms

A mRNA Lipid Nanoparticle Incorporated Nanofiber-hydrogel Composite to Generate a Local Immunostimulatory Niche for Immunotherapy

Value Proposition:· Creates a programmable immunostimulatory niche.· Allows for tailor-made immune responses to vaccines and antigens.· Flexible drug delivery platform enables mRNA therapeutics for infectious diseases and cancers.· Applicable to existing mRNA vaccines for improved efficacy. · Can be utilized for novel...

Published: 9/12/2025 | Inventor(s): Hai-Quan Mao, Yining Zhu, Jingyao Ma, Zhicheng Yao, Christine Wei

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Research Tools, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities > Vaccines, Technology Classifications > Research Tools > Microfluidics