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A mRNA Lipid Nanoparticle Incorporated Nanofiber-hydrogel Composite to Generate a Local Immunostimulatory Niche for Immunotherapy

Value Proposition:· Creates a programmable immunostimulatory niche.· Allows for tailor-made immune responses to vaccines and antigens.· Flexible drug delivery platform enables mRNA therapeutics for infectious diseases and cancers.· Applicable to existing mRNA vaccines for improved efficacy. · Can be utilized for novel...

Published: 3/14/2025 | Inventor(s): Hai-Quan Mao, Yining Zhu, Jingyao Ma, Zhicheng Yao, Christine Wei

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Research Tools, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities > Vaccines, Technology Classifications > Research Tools > Microfluidics

Real-time dose and risk prediction during target and critical structure delineation for radiotherapy

Unmet NeedCurrent radiotherapy treatment planning is done with the assistance of novel software and technology, based on each patient's specific disease and its unique characteristics. There are no current systems available to provide the clinician with information about prior patients' similar disease characteristics that may help inform a...

Published: 3/13/2025 | Inventor(s): Todd Mcnutt, Harry Quon, Scott Robertson, Joseph Moore, Zhi Cheng

Keywords(s): Cancers, Disease Indication, Image Processing Software, Interventional and Surgical Systems, Surgical Navigation

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices