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Paternal Sperm DNA Methylation as a Predictive Marker of Autism Risk

Unmet Need:Autism spectrum disorder (ASD), is a complex neurodevelopmental disorder that refers to a range of conditions characterized by challenges with behavior including social skills, communication, and repetitive behaviors, all of which have ranges and severities that are patient specific. Currently, there are no medical tests such as a scan or...

Published: 6/27/2024 | Inventor(s): Andrew Feinberg, Margaret Fallin

Keywords(s): Autism, Biomarker, Clinical Diagnostics, CNS and Neurological Disorders, Disease Indication, Epigenetic, In Vitro Diagnostics, Methylation, Risk Stratification

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Psychiatry > Autism, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Psychiatry

Angiotensin Receptor as a Therapeutic Target for Autism Disorder

C11584: Diagnosis and of Autism based on Specific Receptor SiteNovelty: This invention is a new method to test pregnant mothers for an increased risk of having autistic children. The identification of this receptor-specific antibody suggests that specific inhibitors, antibodies, or other agents can be used as a therapy for autism.Value Proposition:...

Published: 6/27/2024 | Inventor(s): Tongguang Wang, Christina Morris-Berry, Harvey Singer, Avindra Nath

Keywords(s): Autism, Biomarker, CNS and Neurological Disorders, Disease Indication, Mechanism of Action Biomarker, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Psychiatry > Autism, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Psychiatry, Technology Classifications > Therapeutic Modalities

Hydroxyurea in Autism

C11387: Hydroxyurea for the Treatment of AutismNovelty: This technology employs hydroxyurea (HU), a common treatment for sickle cell disease, to reduce core symptoms, like social responsiveness, in patients of all ages with autism.Value Proposition: Currently, the only available drugs for the treatment of autism are symptomatic. These drugs aim to...

Published: 6/27/2024 | Inventor(s): Kirby Smith, Andrew Zimmerman

Keywords(s): Antagonists/Inhibitors, Autism, CNS and Neurological Disorders, Disease Indication, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Psychiatry > Autism, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Psychiatry, Technology Classifications > Therapeutic Modalities

Cholesterol Treatment of Autism Spectrum Disorder

C10705: Autism Spectrum Disorder: A Treatment ApproachValue Proposition: While there is no known single cause for autism, Inventors have determined that a population of patients with ASD that is not associated with Smith-Lemli-Opitz Syndrome has plasma sterol levels that are outside the typical range. Preliminary studies by the Inventors suggest that...

Published: 6/27/2024 | Inventor(s): Forbes Porter, Elaine Tierney

Keywords(s): Autism, Biomarker, CNS and Neurological Disorders, Disease Indication, Natural compounds, Non-novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics