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Controlled Outgassing of Hyberbarically Loaded Materials for the Delivery of Oxygen and Other Therapeutic Gases in Biomedical Applications

Unmet NeedThe lack of oxygen, or “hypoxia,” can result in severe tissue damage when localized to a region of tissue in the body. Hypoxia also presents a road block to advancement for in vitro tissue engineering because large tissues, organs, and 3D cell cultures quickly develop hypoxia outside the body due to the difficulty in transporting oxygen. Oxygenating...

Published: 9/26/2024 | Inventor(s): Warren Grayson, Colin Cook

Keywords(s): Implantation Method, Implants, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices

Outgassing of Hyperbarically Loaded Polymeric Materials for Biomedical Applications

Unmet NeedTherapeutic gas delivery remains one of the greatest challenges in tissue engineering. Consequently many technologies and approaches have been developed but all lackeffective ways to deliver sufficient therapeutic gas, such as oxygen, to targeted regions within deeper tissue. This invention introduces a means of delivering therapeutic gases...

Published: 9/26/2024 | Inventor(s): Warren Grayson, Colin Cook

Keywords(s): Disease Indication, Drug Delivery Vehicle, Implantation Method, Implanted Device, Implants, Therapeutic Devices, Therapeutic Matter, Therapeutics, Tissue Engineering/Regenerative Devices, Wound Healing

Category(s): Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Clinical and Disease Specializations > Wound Healing

A p105-based NF-(kappa) B Super repressor

C04290: A p105-based NF-(kappa) B Super repressor Technical Details: Nuclear factor (NF)-kB is a family of transcription factors that regulate immune and inflammatory responses, programmed cell death (apoptosis), and developmental processes. In normal cells, NF-kB is latent, and is activated transiently by stimuli and stresses. However, under pathological...

Published: 9/26/2024 | Inventor(s): Li Lin

Keywords(s): Biologics, Cancers, Chemotherapy, Disease Indication, Nucleic Acid, Single, Skin Cancer, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Dermatology, Clinical and Disease Specializations > Oncology > Skin Cancer, Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities > Proteins, Technology Classifications > Therapeutic Modalities > Targets, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities