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Method for Incorporating Internal Polar and Ionizable Groups in Proteins

NOVELTY: This technology comprises a novel method to introduce polar and ionizable groups into the interior of proteins without the loss of protein stability.VALUE PROPOSITION: Currently, the loss of stability related to the introduction of internal ionizable groups has plagued efforts in protein engineering. The disclosed technology overcomes the current...

Published: 3/13/2025 | Inventor(s): Daniel Isom, Bertrand Garcia-Moreno

Keywords(s): Basic Research Biomarker, Cell Signaling, Discovery/Research Tools, Molecular Switches/Receptors, Research Reagent

Category(s): Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Research Tools