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RASAL1 is a Major Tumor Suppressor Gene in Thyroid Cancer

Novel Molecular Diagnostics for Thyroid CancerJHU REF: C12597Invention novelty: This invention has identified a novel tumor suppressor gene, RASAL1 in thyroid cancers. Genetic mutations and epigenetic alterations of the RASAL1 gene can be used for the diagnosis of thyroid cancers.Value Proposition:Papillary and follicular thyroid carcinomas account...

Published: 6/27/2024 | Inventor(s): Dingxie Liu, Michael Xing

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Mechanism-of-action Biomarker, Therapeutic Matter, Therapeutics, Thyroid Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Endocrinology, Clinical and Disease Specializations > Oncology > Thyroid Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities

JHU REF: C12704 - NOVEL STRATEGIES TO OVERCOME MELANOMA DRUG RESISTANCE

Invention novelty: Novel methods for predicting melanoma resistance to BRAF/MEK inhibitors and for treating melanoma cancer patients.Value Proposition:An estimated 76,690 new cases of invasive melanoma will be diagnosed in the US in 2013 and an estimated 9,480 people will die of melanoma in 2013. Although BRAF and MEK inhibitors have proven clinical...

Published: 6/27/2024 | Inventor(s): Dingxie Liu, Michael Xing

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Melanoma, Pharmakodynamic Biomarker, Skin Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Dermatology, Clinical and Disease Specializations > Oncology > Melanoma, Clinical and Disease Specializations > Oncology > Skin Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology

Electro-mechanically Stretched Micro Fibers and Methods of Use

C11956: Improved Stretched Microfiber ProductionNovelty: This technology is a new method for producing stretched microfibers with smaller, more consistent diameters.Value Proposition: While there are numerous known applications for microfibers, current fabrication methods lack a significant amount of control. These primarily consist of using a high...

Published: 6/27/2024 | Inventor(s): Hai-Quan Mao, Shuming Zhang, Xi Liu, Brian Ginn, Sharon Gerecht, Sebastian Barreto Ortiz

Keywords(s): Drug Delivery Vehicle, Hydrogel, Therapeutic Matter, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities