Search Results - thyroid+cancer

11 Results

Sort By:

A Dose-rate Method For Prescribing Radioiodine Treatment In Thyroid Cancer Patients With Lung Metastases

UNMET NEED Radiopharmaceutical therapy (RPT) is an emerging cancer treatment modality in which tumor-targeting molecules are used to deliver radioactive atoms thereby irradiating tumors preferentially over normal organs. Therefore, precision medicine dosimetry is required so that patients are administered the appropriate amount of the RPT for safe...

Published: 3/13/2025 | Inventor(s): George Sgouros, Robert Hobbs, Andrew Prideaux, Hong Song

Keywords(s): Cancers, Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Disease Indication, Physics, Thyroid Cancer

BRAF V600E and TERT Promoter Mutations Cooperatively Identify the Most Aggressive Papillary Thyroid Cancer with Highest Recurrence

BRAF V600E and TERT Promoter Mutations Cooperatively Identify the Most Aggressive Papillary Thyroid Cancer with Highest RecurrenceJHU REF: C12971Invention Novelty: This invention discloses the coexistence of BRAF V600E and TERT C228T mutations as novel molecular marker that defines the most aggressive subgroup of certain cancers (papillary thyroid cancer...

Published: 3/13/2025 | Inventor(s): Michael Xing

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Mechanism-of-action Biomarker, Therapeutic Matter, Therapeutics, Thyroid Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Endocrinology, Clinical and Disease Specializations > Oncology > Thyroid Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities

RASAL1 is a Major Tumor Suppressor Gene in Thyroid Cancer

Novel Molecular Diagnostics for Thyroid CancerJHU REF: C12597Invention novelty: This invention has identified a novel tumor suppressor gene, RASAL1 in thyroid cancers. Genetic mutations and epigenetic alterations of the RASAL1 gene can be used for the diagnosis of thyroid cancers.Value Proposition:Papillary and follicular thyroid carcinomas account...

Published: 3/13/2025 | Inventor(s): Dingxie Liu, Michael Xing

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Mechanism-of-action Biomarker, Therapeutic Matter, Therapeutics, Thyroid Cancer

Analyses of GNAQ, MMP8, AKT3, EGFR and PIK3R1 Mutations in Thyroid Cancers

C11181: Gene Mutations as Diagnostic Targets in CancerNovelty: This discovery identifies the novel oncogenic mutations in various thyroid cancers that can be effective diagnostic markers for thyroid and other human cancers.Value Proposition: Cancer is the second most common cause of death in the industrialized world. Blood tests, imaging and biopsies...

Published: 3/13/2025 | Inventor(s): Michael Xing

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Thyroid Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Endocrinology, Clinical and Disease Specializations > Oncology > Thyroid Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology

IQGAP1 Plays an Important Role in the Invasiveness and Aggressiveness of Thyroid Cancer

C11026: Diagnostic and Prognostic Biomarker for Thyroid CancerNovelty: A copy number mutation for gene IQGAP1 is described that can be used in prognostic and diagnostic tests for cancer, specifically thyroid cancer.Value Proposition: Over the last 40 years the incidence of thyroid cancer has nearly doubled. A highly specific protein mutation will allow...

Published: 3/13/2025 | Inventor(s): Michael Xing

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Prognostic Biomarker, Thyroid Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Endocrinology, Clinical and Disease Specializations > Oncology > Thyroid Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > Prognostics Biomarkers, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology

C10292: Combination Therapy for Thyroid Cancer and Melanoma

Novelty: Application of radioiodine therapy for the treatment of undifferentiated thyroid cancer and melanoma facilitated by induction of iodide-handling genes via dual suppression of PI3K/Akt and MAP kinase pathwaysValue Proposition: Thyroid cancer is typically treated by radioiodine therapy, which exploits the unique capability of thyroid cells to...

Published: 3/13/2025 | Inventor(s): Michael Xing

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Mechanism-of-action Biomarker, Therapeutic Matter, Therapeutics, Thyroid Cancer

Protein Expression Markers for the Detection of Thyroid Cancer Metastasis

C10120: Protein Expression Markers for the Detection of Thyroid Cancer MetastasisValue Proposition: Difficulty in detecting recurrence of thyroid cancer in patients is a recognized medical problem. Present biomarkers for recurring thyroid cancer are not useful in a large proportion of patients with this cancer. These markers have the potential of being...

Published: 3/13/2025 | Inventor(s): Janete Cerutti, Gregory Riggins

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Prognostic Biomarker, Thyroid Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Endocrinology, Clinical and Disease Specializations > Oncology > Thyroid Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > Prognostic Biomarkers, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology

Seventy Two Gene Model for 8 Thyroid Tumor Types

C10073: Seventy Two Gene Model for 8 Thyroid Tumor Types Value Proposition: Thyroid cancer represents 90% of all neuroendocrine malignancies with an estimated annual incidence of 122,800 cases worldwide. Currently, the most useful tool for the diagnosis of thyroid cancer is Fine-needle aspiration biopsy (FNA). This current method is extremely useful...

Published: 3/13/2025 | Inventor(s): Steven Libutti, Martha Zeiger, Nijaguna Prasad, Christopher Umbricht

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Thyroid Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Endocrinology, Clinical and Disease Specializations > Oncology > Thyroid Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology

Alternative Splice Variant Patterns of Human Telomerase Reverse Transcriptase (hTERT) in Thyroid Tumors Distinguish Benign from Malignant

C05018: Alternative Splice Variant Patterns of Human Telomerase Reverse Transcriptase (hTERT) in Thyroid Tumors Distinguish Benign from Malignant Technical Details: Human telomerase reverse transcriptase (hTERT) is activated in thyroid cancer. Despite this, its usefulness as a marker in the distinction of benign from malignant neoplasm has not been...

Published: 3/13/2025 | Inventor(s): Yongchun Wang, Christopher Umbricht, Jeanne Kowalski, Martha Zeiger

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Thyroid Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Endocrinology, Clinical and Disease Specializations > Oncology > Thyroid Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology

Diagnostic Tool for Diagnosing Benign Versus Malignant Thyroid Lesions

C04567: Diagnostic Tool for Diagnosing Benign Versus Malignant Thyroid Lesions Technical Details: Thyroid cancer represents 1% of all malignant diseases and it is estimated that 5-10% of the population will develop a clinically significant thyroid nodule during their lifetime. The best available test for thyroid nodule is fine needle aspiration biopsy...

Published: 3/13/2025 | Inventor(s): Steven Libutti, Chiara Mazzanti, Christopher Umbricht, Martha Zeiger

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Thyroid Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Endocrinology, Clinical and Disease Specializations > Oncology > Thyroid Cancer, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology

1 2