Search Results - george+sgouros

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HER2-positive breast cancer cell lines derived from transgenic HuHER2 mouse model

Unmet NeedPreclinical evaluation of therapeutic agents against metastatic breast cancer require cell lines and animal models that recapitulate clinical metastatic breast cancer.Technology OverviewResearchers at Johns Hopkins University extracted primary mammary gland tumors, purified the epithelial breast cancer cells over a number of passages, and...

Published: 7/4/2024 | Inventor(s): George Sgouros, Sunju Park

Keywords(s): Breast Cancer, Cancers, Cell Lines, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Mouse Cell Lines

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Breast Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools

A Dose-rate Method For Prescribing Radioiodine Treatment In Thyroid Cancer Patients With Lung Metastases

UNMET NEED Radiopharmaceutical therapy (RPT) is an emerging cancer treatment modality in which tumor-targeting molecules are used to deliver radioactive atoms thereby irradiating tumors preferentially over normal organs. Therefore, precision medicine dosimetry is required so that patients are administered the appropriate amount of the RPT for safe...

Published: 7/4/2024 | Inventor(s): George Sgouros, Robert Hobbs, Andrew Prideaux, Hong Song

Keywords(s): Cancers, Computer Systems Based on Biological Models, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Disease Indication, Physics, Thyroid Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Endocrinology, Clinical and Disease Specializations > Oncology > Thyroid Cancer, Technology Classifications > Computers, Electronics & Software, Clinical and Disease Specializations > Oncology