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HER2-positive breast cancer cell lines derived from transgenic HuHER2 mouse model

Unmet NeedPreclinical evaluation of therapeutic agents against metastatic breast cancer require cell lines and animal models that recapitulate clinical metastatic breast cancer.Technology OverviewResearchers at Johns Hopkins University extracted primary mammary gland tumors, purified the epithelial breast cancer cells over a number of passages, and...

Published: 10/4/2024 | Inventor(s): George Sgouros, Sunju Park

Keywords(s): Breast Cancer, Cancers, Cell Lines, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Mouse Cell Lines

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Breast Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools