Search Results - dosed+therapeutic

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Nonviral Gene Transfer to the Suprachoroidal Space

Unmet Need:Gene transfer with adenoassociated viral (AAV) or lentiviral vectors can provide long-term expression in cells that have appropriate receptors for transduction. However, viral vectors induce an immune response making repeated administration impossible and also have limitations to cargo capacity. An alternative is nonviral gene transfer with...

Published: 3/13/2025 | Inventor(s): Peter Campochiaro, Jordan Green, Jikui Shen, Jayoung Kim

Keywords(s): Disease Indication, Dosed Therapeutic, Eye Disorders, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ophthalmology, Technology Classifications > Therapeutic Modalities

Ozonides forms of artemisinins inhibit cytomegalovirus (CMV) replication in vitro and in vivo

INVENTION NOVELTY: This technology involves the use of a derivative of artemisinin as a new therapy for Cytomegalovirus (CMV) infection.VALUE PROPOSITION: CMV infection is recognized as a cause of morbidity and mortality, especially in immunocompromised individuals. CMV is also the most common viral infection in solid organ transplant recipients. Several...

Published: 3/13/2025 | Inventor(s): Ravit Boger, Jonathan Vennerstrom

Keywords(s): Antagonists/Inhibitors, Cytomegalovirus, Disease Indication, Dosed Therapeutic, Infectious Diseases, Novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics, Viral Infections

Category(s): Clinical and Disease Specializations, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Infectious Diseases, Clinical and Disease Specializations > Infectious Diseases > Cytomegalovirus, Clinical and Disease Specializations > Infectious Diseases > Viral Infections