Search Results - jayoung+kim

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Nonviral Gene Transfer to the Suprachoroidal Space

Unmet Need:Gene transfer with adenoassociated viral (AAV) or lentiviral vectors can provide long-term expression in cells that have appropriate receptors for transduction. However, viral vectors induce an immune response making repeated administration impossible and also have limitations to cargo capacity. An alternative is nonviral gene transfer with...

Published: 3/13/2025 | Inventor(s): Peter Campochiaro, Jordan Green, Jikui Shen, Jayoung Kim

Keywords(s): Disease Indication, Dosed Therapeutic, Eye Disorders, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ophthalmology, Technology Classifications > Therapeutic Modalities

Synthesis of poly(β-amino ester)-co-polyethylene glycol (PEG-PBAE-PEG) polymer for gene and drug delivery

Non-viral vectors are widely investigated due to their ability to safely and effectively deliver exogenous genes and potentially cure diseases of genetic origin. Much portion of the ongoing research in the field is also dedicated to further optimize the existing vectors for in vivo applications. This work describes new compositions of matter of polyethylene...

Published: 3/13/2025 | Inventor(s): Jordan Green, Jayoung Kim, Stephany Tzeng

Keywords(s): Drug Delivery Vehicle, Drug Delivery Vehicle Synthesis Method, Polymers, Therapeutic Matter, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Dendrimers & Polymers, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities