Search Results - eniko+papp

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Biomarkers of Therapeutic Response in Ovarian Cancer

Unmet NeedOvarian cancer is the most common cause of death among gynecological cancers and is associated with poor outcomes and low overall survival rates. The current standard of care involves surgical resection of the solid tumor, followed by chemotherapy. This type of therapy has limited success among women with advanced disease, and often results...

Published: 3/14/2025 | Inventor(s): Victor Velculescu, Robert Scharpf, Eniko Papp, Dorothy Hallberg, Dennis Slamon, Gottfried Konecny

Keywords(s): Cancers, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Ovarian Cancer, Target-based Screening Tool

Category(s): Clinical and Disease Specializations > Oncology > Ovarian Cancer

Genetic Alterations Related to Anti-EGFR Therapeutic Response

Unmet Need:Colorectal cancer is the third most common cancer worldwide, with 1.2 million patients diagnosed annually. In late-stage colorectal cancer, the most commonly used targeted therapies are monoclonal antibodies, which prevent epidermal growth factor receptor (EGFR) activation. Several studies have identified alterations in KRAS and other genes...

Published: 3/13/2025 | Inventor(s): Livio Trusolino, Andrea Bertotti, Victor Velculescu, Vilmos Adleff, Eniko Papp

Keywords(s): Biomarker, Cancers, Colorectal Cancer, Disease Indication, Pharmakodynamic Biomarker, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Oncology > Colorectal Cancer