Search Results - fungal+infections

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Unmet NeedIncreasingly, invasive mold infections have been recognized in people who are immune compromised by genetic conditions, aging, other infections (e.g. HIV) and modern medicine (e.g. transplantation). Moreover, increasing evidence points to the role of these organisms as causes of environmental toxicities and industrial spoilage. An over-abundance...

Published: 6/27/2024 | Inventor(s): Kieren Marr, Jennifer Pluznick, Victoria Halperin-Kuhns

Keywords(s): Assay, Biomarker, Clinical Diagnostics, Disease Indication, Environmental Sensing, Fungal Infections, Imaging and Sensing Systems, In Vitro Diagnostics, Mechanism-of-action Biomarker, Sensing Modality, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Fungal Infections, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Research Tools, Technology Classifications > Therapeutic Modalities

Novel Anti-fungal Inhibitors

Unmet NeedIndividuals with impaired immunity, including those with advanced HIV infection, organ transplants, and on immunosuppressive regimens are susceptible to major fungal pathogens, such as Cryptococcus neoformans and Candida albicans. Cryptococcus neoformans is particularly problematic for AIDS patients. Over a million people worldwide suffer...

Published: 6/27/2024 | Inventor(s): Jurgen Bosch, Arturo Casadevall, Eric Jung

Keywords(s): Antagonists/Inhibitors, Disease Indication, Fungal Infections, Novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Fungal Infections, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities

Interferon-gamma Release Assays for Diagnosis of Invasive Fungal Infections

Some invasive fungal infections that are problematic to humans are those that are difficult to diagnose. This is particularly true when fungal antigens are hard to detect and/or culture does not reveal the cause of infection. We have developed assays to detect infection with pathogenic fungi by measuring release of interferon-gamma by the infected host...

Published: 6/27/2024 | Inventor(s): Kieren Marr

Keywords(s): Assay, Clinical Diagnostics, Disease Indication, Fungal Infections, In Vitro Diagnostics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Fungal Infections, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Research Tools