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Unmet NeedThe miR-143/145 microRNA cluster has been implicated in colon cancer and other epithelial tumors, but investigation of its role in pathogenesis requires a research tool in which miR-143/145 expression can be modulated in specific cell types. Technology OverviewJohns Hopkins researchers generated a conditional knockout allele for the miR-143/145...

Published: 6/20/2024 | Inventor(s): Joshua Mendell, Raghu Chivukula, Guanglu Shi

Keywords(s): Cell Lines, Discovery/Research Tools, In Vitro Research Tool, Mouse Cell Lines

Category(s): Technology Classifications > Research Tools > Animal Models