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Self-Assembling Antiviral Prodrugs for Long-Acting Treatment of Chronic HIV Infections

Unmet Need / Invention Novelty: The need for long-acting HIV drugs arises from challenges such as pill burden, side effects, and stigma, which contribute to inconsistent use and reduced effectiveness. A long-acting antiretroviral formulation could enhance treatment adherence, reduce disease transmission, and better support populations facing barriers...

Published: 3/14/2025 | Inventor(s): Honggang Cui, Charles Flexner, Maya Monroe, Han Wang

Keywords(s):

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Peptides, Clinical and Disease Specializations > Infectious Diseases > HIV, Clinical and Disease Specializations > Infectious Diseases > HIV/AIDS, Clinical and Disease Specializations > Infectious Diseases > Hepatitis B Virus, Clinical and Disease Specializations > Infectious Diseases > Viral Infections

Implantable Multilayer 3D Scaffold Consisting of Highly Aligned Electrospun Fibers for Neuronal Regeneration Applications

C10716: Implantable Multilayer 3D Scaffold for Neuronal Regeneration ApplicationsValue Proposition:The multilayer 3D conduit is a superior candidate for nerve repair and clinical regeneration applications.• The novel wall structure made of double-sided fibers increases the opportunities for cell migration so that more cells populate the regenerating...

Published: 3/13/2025 | Inventor(s): Jared Cregg, Han Wang, Michael Mullins, Martin Oudega, Ryan Gilbert, Andres Hurtado

Keywords(s): CNS and Neurological Disorders, Disease Indication, Drug Delivery Vehicle, Hydrogel, Implanted Device, Implants, Spinal Cord Injury, Therapeutic Devices, Therapeutic Matter, Therapeutics, Tissue Engineering/Regenerative Devices

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology > Spinal Cord Injury, Clinical and Disease Specializations > Traumatic Injury, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Clinical and Disease Specializations > Neurology, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Dendrimers & Polymers, Technology Classifications > Medical Devices > Regenerative Medicine