Search Results - hideki+nakamura

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Chemically Inducible Hetero-trimerization Tool

Value Proposition· Chemically Inducible Trimerization (CIT) for introducing a third recruitable component· Addition of rapamycin through rational splitting of FKBP and FRB leads to efficient trimerization· Has robust cellular applications e.g., inducing tri-organellar plasma membrane-ER-mitochondria junctionsUnmet Need There have...

Published: 6/12/2026 | Inventor(s): Takanari Inoue, Di Wu, Masaki Kikuchi, Onur Dagliyan, Hideki Nakamura, Nikolay Dokholyan, Takashi Umehara

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Category(s): Technology Classifications > Research Tools > Proteins, Ligands & Receptors

Intracellular actuator that generates and manipulates physical force in living cells

Value PropositionPhysical force generation inside living cells via light irradiation and chemical treatmentThis research tool can be applied to arbitrary intracellular targets in a specific and spatiotemporal mannerSystem is built on peptide derived from protein ActA, which, through DNA sequence modification, increased expression in mammalian cells...

Published: 6/12/2026 | Inventor(s): Takanari Inoue, Hideki Nakamura, Elmer Rho

Keywords(s): Discovery/Research Tools, Peptides, Recombinant Proteins, Research Reagent, Translational Research Biomarker

Category(s): Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Imaging, Technology Classifications > Research Tools > Vectors & Plasmids