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Augmentation of Endocardial Thromboresistance

C04927: Augmentation of Endocardial Thromboresistance Technical Details: A critical function of the endocardium is to maintain local thromboresistance by providing an anticoagulant surface. Thrombomodulin, is expressed on the surface of the endocardium endothelial cells and is the key component of the anticoagulant protein C pathway, and thus is critical...

Published: 6/27/2024 | Inventor(s): Navin Kapur, Jeffrey Rade

Keywords(s): Biologics, Cardiovascular Diseases, Cell Therapy, CNS and Neurological Disorders, Disease Indication, Protein, Single, Stroke, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology > Stroke, Technology Classifications > Therapeutic Modalities > Cell Therapies, Clinical and Disease Specializations > Neurology, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Biologics, Clinical and Disease Specializations > Cardiovascular

Genetic Engineering of Autologous Vein Grafts with thrombomodulin-Expressing Vectors to Resist thrombosis, Neointimal Hyperplasia and Atherosclerosis

C03579: Genetic Engineering of Autologous Vein Grafts with thrombomodulin-Expressing Vectors to Resist thrombosis, Neointimal Hyperplasia and Atherosclerosis Technical Details: Autologous vein grafts are the most widely used conduits for coronary and peripheral arterial bypass surgery. Compared to arterial grafts, vein grafts suffer significantly...

Published: 6/27/2024 | Inventor(s): Jeffrey Rade

Keywords(s): Atherosclerosis, Cardiovascular Diseases, Disease Indication, Gene Therapy, Natural compounds, Neointimal hyperplasia, Non-novel, Predicted Novelty, Single, Therapeutic Matter, Therapeutics, Therapy Type, Thrombosis

Category(s): Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Cardiovascular, Clinical and Disease Specializations > Cardiovascular > Atherosclerosis