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B7-DC Knockout Mice
Detailed DescriptionThe Pdcd1lg2 gene encodes the costimulatory molecule PD-L2 which is expressed in dendritic cells (DCs). To establish the mouse line Stk 017515 - B6N.129(Cg)-Pdcd1lg2tm2Dmp/J which is deficient for PD-L2, a genomic fragment containing exon 2 of the programmed cell death 1 ligand 2 (Pdcd1lg2 which encodes PD-L2) gene, two of loxP sites...
Published: 3/14/2025
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Inventor(s):
Drew Pardoll
,
Lieping Chen
,
Kevin Gorski
,
Haruo Tsuchiya
,
Tahiro Shin
Keywords(s):
Discovery/Research Tools
,
In Vivo Research Tool
,
Knock Out Mouse Model
,
Mouse Model
,
Translational Research Biomarker
Category(s):
Technology Classifications > Research Tools > Animal Models
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