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Use of Bacteria, Bacterial Products, and other Immunoregulatory Entities in Combination with Anti-CTLA-4 and/or Anti-PD-1 Antibodies to Treat Solid Tumor Malignancies

Combined Therapeutic Method for Solid TumorJHU REF: [C12570]Invention novelty: This technology is a combination therapy method including a tumor-specific bacterium and antibodies that boost tumor immune response.Value PropositionWorldwide cancer affects more than 12 million people each year. This number is expected to increase to 14 million each year...

Published: 6/27/2024 | Inventor(s): Kenneth Kinzler, Bert Vogelstein, KiBem Kim, Shibin Zhou

Keywords(s): Antibodies, Biologics, Cancers, Combination, Disease Indication, Immunotherapy/ Immunotherapy, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Whole cell

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Cell Therapies, Technology Classifications > Therapeutic Modalities > Immunotherapies