Search Results - mi-kyung+shin

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Supramolecular Hydrogel Applications to the Carotid Bodies to Treat Hypertension and Sleep Apnea in Obesity

Unmet NeedOver one-third of adults in the U.S. (36.5%) have obesity. Further, obesity leads to increased cardiovascular morbidity and mortality via multiple adverse mechanisms that include increased prevalence and severity of hypertension (often resistant to treatment) and obstructive sleep apnea (OSA). Currently, no pharmacotherapy exists for OSA....

Published: 7/4/2024 | Inventor(s): Vsevolod Polotsky, Honggang Cui, Roxana Mitrut, Mi-kyung Shin

Keywords(s): Cardiovascular Diseases, CNS and Neurological Disorders, Disease Indication, Drug Delivery Vehicle, Hypertension, Metabolic Disorders, Obesity, Peptides/Prodrugs, Sleep Apnea, Sleep Disorders, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Peptides, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Clinical and Disease Specializations > Cardiovascular > Hypertension, Clinical and Disease Specializations > Sleep Disorders > Sleep Apnea, Clinical and Disease Specializations > Obesity

A Microfabricated Multiple Actuation Device for Mechanical Conditioning of 3D Microtissues

We have recently demonstrated an approach that enables mechanical stimulation of microtissues via magnetic actuation of magnetic microspheres bonded to one of the cantilevers in each device (ALL THREE ZHAO REFS). This has notably allowed measurement of the mechanical stiffness of such constructs, and hence analysis of the relative contribution of cells...

Published: 7/4/2024 | Inventor(s): Fan Xu, Ruogang Zhao, Tristin Metz, Alan Liu, Yu Shi, Daniel Reich

Keywords(s): Implanted Device, Implants, Therapeutic Devices, Therapeutic Method, Therapeutics, Tissue Engineering/Regenerative Devices

Category(s): Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Therapeutic Modalities, Technology Classifications > Medical Devices