Search Results - hypertension

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A Novel and Unique Set of Human Antibodies to Human Resistin and to Human Resitin-like Molecule Beta (RELMB) that can be used to Target these Proteins in Human Disease

Unmet NeedAutoinflammatory responses, your body’s innate defense mechanism against infections and stressors, can become overactive and cause chronic inflammation in various tissues and organs. Inflammatory diseases affect more than 200 million people worldwide and include pulmonary hypertension, scleroderma, rheumatoid arthritis, pulmonary fibrosis,...

Published: 3/13/2025 | Inventor(s): Roger Johns

Keywords(s): Antibodies, Biologics, Cardiovascular Diseases, Disease Indication, Hypertension, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Technology Classifications > Therapeutic Modalities > Antibodies, Technology Classifications > Therapeutic Modalities > Biologics, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Cardiovascular > Hypertension

HBP SCP: Hypertension Self-Care Profile

An express license for this technology is available via JHTV's online licensing portal.Unmet NeedSignificant economic burdens arise from multiple complications and premature mortality from hypertension (HBP) for hypertensive individuals, their families, and society. Despite numerous published HBP management and behavioral treatment guidelines, blood...

Published: 3/13/2025 | Inventor(s): Hae-Ra Han

Keywords(s): Cardiovascular Diseases, Disease Indication, Healthcare Management, Hypertension, Operations Management, Readiness Assessment Tools

Category(s): Technology Classifications > Computers, Electronics & Software > Healthcare IT, Clinical and Disease Specializations > Cardiovascular > Hypertension, Express Licensing

Supramolecular Hydrogel Applications to the Carotid Bodies to Treat Hypertension and Sleep Apnea in Obesity

Unmet NeedOver one-third of adults in the U.S. (36.5%) have obesity. Further, obesity leads to increased cardiovascular morbidity and mortality via multiple adverse mechanisms that include increased prevalence and severity of hypertension (often resistant to treatment) and obstructive sleep apnea (OSA). Currently, no pharmacotherapy exists for OSA....

Published: 3/13/2025 | Inventor(s): Vsevolod Polotsky, Honggang Cui, Roxana Mitrut, Mi-kyung Shin

Keywords(s): Cardiovascular Diseases, CNS and Neurological Disorders, Disease Indication, Drug Delivery Vehicle, Hypertension, Metabolic Disorders, Obesity, Peptides/Prodrugs, Sleep Apnea, Sleep Disorders, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Peptides, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Clinical and Disease Specializations > Cardiovascular > Hypertension, Clinical and Disease Specializations > Sleep Disorders > Sleep Apnea, Clinical and Disease Specializations > Obesity

Circulating Pulmonary Hypertension Biomarker

UNMET NEEDPulmonary hypertension (PH) can result from a number of changes in the cardiorespiratory system that cause increased pulmonary arterial pressure. Hemodynamic evaluation is one of the best diagnostics, but pulmonary artery catheterization is expensive and invasive; therefore biomarkers that diagnosis and/or predict PH are needed. Some of...

Published: 3/13/2025 | Inventor(s): Jun Yang, Allen Everett

Keywords(s): Biomarker, Cardiovascular Diseases, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, Hypertension, In Vitro Diagnostics, Lung Disorders, Pulmonary Hypertension

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Hypertension, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Diagnostics

Biomarkers of Pulmonary Hypertension

C11797: Blood Test Biomarkers for Pulmonary Arterial HypertensionNovelty: This invention is a novel set of circulating biomarkers found in serum and plasma which can be used for diagnostic and prognostic testing of Pulmonary Arterial Hypertension (PAH).Value Proposition: Currently, the first line of treatment for PAH is prescribing vasodilators, which...

Published: 3/13/2025 | Inventor(s): Zongming Fu, Allen Everett

Keywords(s): Biomarker, Cardiovascular Diseases, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, Hypertension, In Vitro Diagnostics, Prognostic Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Hypertension, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > Prognostics Biomarkers, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Diagnostics

Hypoxia-induced Mitogenic Factor

C04061: Hypoxia-induced Mitogenic FactorValue Proposition: Johns Hopkins University is seeking licensees for Hypoxia-Induced Mitogenic Factor (HIMF/ FIZZ1/RELM), a cell line expressing tagged HIMF, antibodies to HIMF and receptor. HIMF provides a wide array of novel biomarkers and therapeutic targets for lung, vascular, cardiac and inflammatory diseases,...

Published: 3/13/2025 | Inventor(s): Xingwu Teng, Dechun Li, Roger Johns

Keywords(s): Biomarker, Cardiovascular Diseases, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, Hypertension, In Vitro Diagnostics, Inflammatory Disorders, Lung Disorders