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Enzymatic labeling of poly(ADP-ribose) polymer and ADP-ribosylated proteins
Unmet NeedDysregulation of ADP-ribosylation, the process of adding ADP-ribose groups onto proteins, has been implicated in the pathogenesis of cancer, viral infection, and neurodegeneration. To date, three drugs that inhibit polyADP-ribose polymerases (PARP) have been approved by the FDA to treat ovarian and other cancers. Though a promising new therapeutic...
Published: 3/13/2025
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Inventor(s):
Anthony Leung
,
Yoshinari Ando
,
Robert McPherson
,
Elad Elkayam
,
Mohsen Badiee
Keywords(s):
Basic Research Biomarker
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Discovery/Research Tools
,
Labels/Markers
,
Research Reagent
Category(s):
Technology Classifications > Diagnostics > Biomarkers
,
Technology Classifications > Research Tools
,
Technology Classifications > Diagnostics
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