Search Results - richard+jones

2 Results

Sort By:

Aldehyde Dehydrogenase Activity Distinguishes Leukemia Stem Cells from Normal Hematopoietic Stem Cells in Acute Myeloid Leukemia

Using the methods of the present invention, intermediate (int) levels of aldehyde dehydrogenase (ALDH) activity reliably distinguished leukemic CD34+CD38? cells capable of engrafting immunodeficient mice, from residual normal hematopoietic stem cells that exhibited relatively higher ALDH activity. Minimal residual disease (MRD) detected during complete...

Published: 6/27/2024 | Inventor(s): Richard Jones, Jonathan Gerber

Keywords(s): Acute Myeloid Leukemia, Biomarker, Cancers, Clinical Diagnostics, Disease Indication, Hematologic Malignancies, In Vitro Diagnostics, Leukemia, Mechanism-of-action Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Hematology, Clinical and Disease Specializations > Oncology > Acute Myeloid Leukemia, Clinical and Disease Specializations > Oncology > Hematologic Malignancies, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology

Identification of Circulating Cancer Stem Cells in Patients with B Cell Malignancies

C10205: Methods for Detecting and Monitoring Circulating Cancer Stem CellsValue Proposition: • Novel method to the quantify cancer stem cells from peripheral blood of patients • Method to identify cells with clonogenic potential to mediate tumor regrowth that are relatively chemoresistant • Novel techniques to monitor cancer...

Published: 6/27/2024 | Inventor(s): Richard Jones, Carol Huff, William Matsui

Keywords(s): Assay, Cancers, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Diagnostics, Technology Classifications > Research Tools