Search Results - srinivasagopalan+sampathkumar

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Deconvolution and Selective Control of Specific Biological Activities with Partially Acylated and Mixed SCFA-derivatized Monosaccharide-SCFA Hybrid Molecules

Value Proposition: This invention solves two problems inherent with the use of Short Chain Fatty Acid (SCFA)-monosaccharide hybrid molecules to modulate cellular activity. The first problem is the toxicity of former versions of these compounds. The current invention uses structure activity relationships as it has been discovered to either enhance or...

Published: 3/13/2025 | Inventor(s): Christopher Weier, Srinivasagopalan Sampathkumar, Christopher Campbell, Udayanath Aich, Sean Choi, Michael Meledeo, Kevin Yarema

Keywords(s): Novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities

Short Chain Fatty Acid (SCFA) - Carbohydrate Bifunctional Hybrid Molecules with Novel Anti-cancer Properties

C04704: Short Chain Fatty Acid (SCFA) - Carbohydrate Bifunctional Hybrid Molecules with Novel Anti-cancer Properties Value Proposition: Butyrate, a natural short chain fatty acid (SCFA), is well-established to have anti-cancer properties via its ability to induce cell cycle arrest and apoptosis in cancer cells. Currently, several clinical trials are...

Published: 3/13/2025 | Inventor(s): Mark Jones, Udayanath Aich, Srinivasagopalan Sampathkumar, Christopher Campbell, Kevin Yarema

Keywords(s): Biologics, Cancers, Carbohydrates, CNS and Neurological Disorders, Disease Indication, Parkinson's Disease, Single, Targeted Therapy, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology > Parkinson's Disease, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Targets, Clinical and Disease Specializations > Neurology, Technology Classifications > Therapeutic Modalities