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Predictive Algorithms for MISKD Clinical Decision Support System

Unmet NeedChildren hospitalized with SARS-Cov-2 infection are at risk for two similar inflammatory syndromes: Kawasaki disease (KD), and multi-system inflammatory syndrome in children (MIS-C). However, current clinical diagnostic standards for these two conditions have considerable overlap, which can lead to misdiagnosis and suboptimal treatment and...

Published: 6/27/2025 | Inventor(s): Cedric Manlhiot, Bhargava Kumar Chinni, Shelby Kutty

Keywords(s):

Category(s): Clinical and Disease Specializations, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Clinical and Disease Specializations > Infectious Diseases > Covid-19, Clinical and Disease Specializations > Inflammation

Accelerating Numerical Methods with AI-Based Surrogate Models

Value Proposition: Efficient modeling of dynamic phenomena with negligible error rates below 1% Reduced computational demand, not dependent on large datasets Utility across different domains and scalable to multiscale challenges Applicable to life sciences, material science, and engineering sectors Unmet Need: Accurate modeling of material...

Published: 6/27/2025 | Inventor(s): Somdatta Goswami, Wei Wang

Keywords(s):

AR CPR: Augmented Reality System to Improve Cardiopulmonary Resuscitation

Unmet NeedAccording to the Pearlman School of Medicine, pediatric in-hospital cardiac arrest (IHCA) occurs frequently and has a high mortality rate. Each year more than 15,000 children receive cardiopulmonary resuscitation (CPR) for cardiac arrest during hospitalization in the United States (Topjian, et al., 2021). As many as 80% to 90% survive the...

Published: 6/27/2025 | Inventor(s): Therese Canares, Justin Jeffers, Keith Kleinman, Blake Schreurs, James Dean, Brandon Scott

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Sensors, Clinical and Disease Specializations > Pediatrics, Clinical and Disease Specializations > Cardiovascular > Cardiac Arrest, Technology Classifications > Medical Devices > Cardiology

AI-Powered Brain Tumor Prognosis Tool Post-Surgery

Value Proposition: Combines MRI imaging and clinical variables for a comprehensive and accurate prediction of brain tumor outcomes and can automates complex analyses to save time for clinicians while supporting personalized patient counseling and optimized treatment strategies. Demonstrates proven accuracy through validation on 600 glioblastoma...

Published: 6/27/2025 | Inventor(s): Julian Gendreau, Yuncong Mao, Linda Tang, Melanie Alfonzo Horowitz, Saket Myneni, Jacob Gould, Karim Ahmed

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Glioblastoma, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools

Parameterized denoising network

Unmet NeedThere exists a wide array of strategies for noise reduction in x-ray computed tomography (CT), most of which provide sufficient efficacy in providing a more optimal output. However, current machine learning approaches are developed to provide a singular output of the best solution. This, however, is limiting as certain applications require...

Published: 6/27/2025 | Inventor(s): Joseph Stayman, Jianan Gang, Jeremias Sulam, Wenying Wang

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence

Interpretable Machine Learning by Composing Queries

Unmet NeedArtificial intelligence (AI), with its ability to computationally carry out complex tasks quickly, has the potential to revolutionize many fields. However, its real-world use is currently limited by its lack of interpretability: it is difficult to understand how AI models generate their outputs. This is especially important in risk-averse...

Published: 6/27/2025 | Inventor(s): Rene Vidal, Aditya Chattopadhyay, Donald Geman, Benjamin Haeffele

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence

Personalized Care for Patients with Retinal Diseases

Unmet NeedAccording to the National Institute of Health, neovascular (wet) age-related macular degeneration (nAMD) is the most common cause of visual impairment among elderly patients in developed countries, and is predicted to increase globally from 196 million patients in 2020 to 288 million by 2040. Our current management of nAMD has two major limitations....

Published: 6/27/2025 | Inventor(s): Tin Yan Liu, Craig Jones

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Healthcare IT, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Machine Learning, Clinical and Disease Specializations > Ophthalmology > Age-Related Macular Degeneration

Antibody Structure Prediction from Pre-trained Language Model (IgFold)

Inventor(s): Jeffrey Ruffolo and Jeffrey Gray Unmet Need: Antibodies are able to bind a diverse set of antigens and have become critical therapeutics and diagnostic molecules. Antibody binding is facilitated by a set of six hypervariable loops that are diversified through genetic recombination and mutation. An accurate structural model of the hypervariable...

Published: 6/27/2025 | Inventor(s): Jeffrey Gray, Jeffrey Ruffolo

Keywords(s):

Category(s): Copyright, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Research Tools > Antibodies

Continuous Ultrasound Imaging for Monitoring of Structures and Their Function under Normal and Pathologic Conditions

Continuous Ultrasound Imaging with AI for Diagnosis of Deep Vein Thrombosis (DVT) JHU Ref #: C17510 Value PropositionContinuous ultrasound imaging of blood vessels in the leg to detect abnormalities in blood flow.This technology uses artificial intelligence (AI) to monitor ultrasound images and assess the risk and diagnose deep vein thrombosis early.Current...

Published: 6/27/2025 | Inventor(s): Aliaksei Pustavoitau, Amir Manbachi, Kaushik Sampath, James Wissman, Haley Abramson, Joshua Punnoose, Kelley Leadingham

Keywords(s):

Category(s): Technology Classifications, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices

Machine Learning Algorithm for Delirium Prediction in the Intensive Care Unit

Unmet NeedDelirium is a potentially preventable and often reversible disorder of impaired cognition. It is common in the intensive care unit (ICU), with an overall prevalence of 32.3%. However, the prevalence is dependent on the type of patients. For example, among ventilated burn patients, the prevalence is 77%, and among mechanically ventilated patients,...

Published: 6/27/2025 | Inventor(s): Robert Stevens, Kirby Gong, Akaash Sanyal, Joanna Guo, Ryan Lu, Teya Bergamaschi, Han Kim

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology > Dementia, Clinical and Disease Specializations > Neurology > Cognitive Impairment, Clinical and Disease Specializations > Neurology, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Diagnostics > Prognostic Biomarkers

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