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Personalized Care for Patients with Retinal Diseases

Unmet NeedAccording to the National Institute of Health, neovascular (wet) age-related macular degeneration (nAMD) is the most common cause of visual impairment among elderly patients in developed countries, and is predicted to increase globally from 196 million patients in 2020 to 288 million by 2040. Our current management of nAMD has two major limitations....

Published: 6/28/2024 | Inventor(s): Tin Yan Liu, Craig Jones

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Healthcare IT, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Machine Learning, Clinical and Disease Specializations > Ophthalmology > Age-Related Macular Degeneration

Antibody Structure Prediction from Pre-trained Language Model (IgFold)

Inventor(s): Jeffrey Ruffolo and Jeffrey Gray Unmet Need: Antibodies are able to bind a diverse set of antigens and have become critical therapeutics and diagnostic molecules. Antibody binding is facilitated by a set of six hypervariable loops that are diversified through genetic recombination and mutation. An accurate structural model of the hypervariable...

Published: 6/28/2024 | Inventor(s): Jeffrey Gray, Jeffrey Ruffolo

Keywords(s):

Category(s): Copyright, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Research Tools > Antibodies

Continuous Ultrasound Imaging for Monitoring of Structures and Their Function under Normal and Pathologic Conditions

Continuous Ultrasound Imaging with AI for Diagnosis of Deep Vein Thrombosis (DVT) JHU Ref #: C17510 Value PropositionContinuous ultrasound imaging of blood vessels in the leg to detect abnormalities in blood flow.This technology uses artificial intelligence (AI) to monitor ultrasound images and assess the risk and diagnose deep vein thrombosis early.Current...

Published: 6/28/2024 | Inventor(s): Aliaksei Pustavoitau, Amir Manbachi, Kaushik Sampath, James Wissman, Haley Abramson, Joshua Punnoose, Kelley Leadingham

Keywords(s):

Category(s): Technology Classifications, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices

Machine Learning Algorithm for Delirium Prediction in the Intensive Care Unit

Unmet NeedDelirium is a potentially preventable and often reversible disorder of impaired cognition. It is common in the intensive care unit (ICU), with an overall prevalence of 32.3%. However, the prevalence is dependent on the type of patients. For example, among ventilated burn patients, the prevalence is 77%, and among mechanically ventilated patients,...

Published: 6/28/2024 | Inventor(s): Robert Stevens, Kirby Gong, Akaash Sanyal, Joanna Guo, Ryan Lu, Teya Bergamaschi, Han Kim

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology > Dementia, Clinical and Disease Specializations > Neurology > Cognitive Impairment, Clinical and Disease Specializations > Neurology, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Diagnostics > Prognostic Biomarkers

A System for the Automated Classification of Disease Tissue in Molecular Imaging Studies utilizing Convolutional Neural Networks with User-Selectable Sensitivity and Specificity

Unmet NeedMedical imaging is an important diagnostic tool used for the detection of a wide array of clinical conditions. The application of Artificial Intelligence (AI) and Deep Learning (DL) is being developed to assist medical imaging professionals manage the ever-growing number of images which they must interpret in their research and clinical practice....

Published: 6/28/2024 | Inventor(s): Jeffrey Leal

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Healthcare IT, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging

CloneRetriever: An Automated Algorithm to Identify B-cell and T-cell Gene Rearrangements by Next-Generation Sequencing

Unmet NeedIn the U.S., there are an estimated 1,297,027 people living with blood cancers (leukemia, lymphoma or myeloma), with an additional 178,520 people expected to be diagnosed each year (see Leukemia & Lymphoma Society). Diagnostics tools that utilize next-generation sequencing (NGS) technologies are often performed to identify gene rearrangements...

Published: 6/28/2024 | Inventor(s): Rena Xian, Eitan Halper-Stromberg, Richard Ambinder

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > Prognostic Biomarkers

Quantitative Human Motion Analysis using Video-based Pose Estimation

Unmet NeedHuman gait analysis is now common in many fields of clinical and basic research, but gold standard approaches – e.g., three-dimensional motion capture, instrumented mats or footwear, and wearables – are often expensive, immobile, data-limited, and/or require specialized equipment or expertise for operation, furthermore limiting the access...

Published: 6/28/2024 | Inventor(s): Ryan Roemmich, Jan Stenum

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology > Multiple Sclerosis, Clinical and Disease Specializations > Neurology > Parkinson’s Disease, Clinical and Disease Specializations > Neurology > Stroke, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging

Automated Surgical Learning and Debriefing Platform

Unmet NeedA cataract is a condition denoted by the blurring of the lens of the eye that accounts for 51% of blindness and 33% of visual impairments worldwide (see WHO). The number of people in the U.S. with cataracts is expected to double from 24.4 million in 2010 to a projected 50 million in 2050 (see NIH). Surgery is the only corrective treatment...

Published: 6/28/2024 | Inventor(s): Shameema Sikder, Satyanarayana Vedula, Gregory Hager, Tae Soo Kim, Chien-Ming Huang, Kristen Park, Anand Malpani, Bohua Wan

Keywords(s):

Category(s): Clinical and Disease Specializations > Ophthalmology, Clinical and Disease Specializations > Surgery, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Medical Devices > Surgery, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Research Tools > Surgical

Segmenting retinal OCT images with inter-B-scan and longitudinal information

Unmet NeedA recent study by the National Multiple Sclerosis Society found that nearly one million people are living with multiple sclerosis (MS) in the United States, making it the most common immune-mediated inflammatory demyelinating disease of the nervous system. Due to few disease-specific characteristic symptoms and the varied pace of disease progression...

Published: 6/28/2024 | Inventor(s): Jerry Prince, Yufan He, Aaron Carass

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology > Multiple Sclerosis, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Diagnostics > Companion Diagnostics, Technology Classifications > Medical Devices > Imaging

Cognitive Load Aware User Interfaces for Mixed Reality Environments

Unmet NeedIntelligent personal assistants (IPAs) – like Alexa, Cortana, Siri, Bixby, or Google Assistant – represent an emerging method by which customers can interact with technology in a more natural, conversational manner. IPAs that fail to adapt to the cognitive or emotional states of their users – for example, overloading users with information...

Published: 6/28/2024 | Inventor(s): Mathias Unberath, Kinjal Shah, Wenhao Gu

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Sensors

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