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Apparatus and Method for modular ultrasound and photoacoustic imaging and interactive guidance using a position-tracked modular imaging framework

Value Proposition· Wearable ultrasound system that is adaptable to different patient physiologies and ages.· Allows for longitudinal and non-invasive monitoring of internal organs of critical care patients.· Applicable across a broad range of organ systems and disease indications.· Simulation-aided interactive guidance simplifies...

Published: 3/14/2025 | Inventor(s): Jeeun Kang, Emad Boctor, Ananya Tandri

Keywords(s):

Category(s): Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Imaging

Non-contact Ultrasound Tomography Imaging System

Multifunctional 3D ultrasound imaging systemJHU Ref #: C17859Value Proposition:· Generation of high resolution 3D images for detection and diagnosis of diseases.· Overcomes previous required use of media (water) to image.· Media-less imaging ability allows for integration of other imaging techniques (MRI, PET, CT). Unmet Need· The...

Published: 3/14/2025 | Inventor(s): Jeeun Kang, Emad Boctor, Hyunwoo Song, Yixuan Wu

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Breast Cancer, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging

Imaging Mannose Overexpression for Grading Glioblastoma Aggressiveness

Value Proposition:Label-free MRI method that requires no regulatory approval or additional drug developmentCan significantly decrease the time between initial diagnosis and follow-up treatment, as tumor aggressiveness could be predicted during the initial diagnostic MRI, improving patient survival rates and post-treatment evaluationNon-invasive diagnostic...

Published: 3/14/2025 | Inventor(s): Jeff Bulte, Behnaz Ghaemi

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology > Brain Cancer, Clinical and Disease Specializations > Oncology > Glioblastoma, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Diagnostics > Prognostic Biomarkers, Technology Classifications > Research Tools > Imaging

18F-Labeled PET Radiotracers for Imaging Neuroinflammation in the Brain

Value Proposition:· Quantification and PET imaging of microglial cells in the brain· Diagnostic for neuroinflammatory disorders – Alzheimer’s and MS· Favorable compound half-life enables shipping· Potential for non-CNS applications Technology DescriptionResearchers at Johns Hopkins have developed a series of Positron Emission Tomography...

Published: 3/14/2025 | Inventor(s): Martin Pomper, Deepankar Das, Andrew Horti, Wojciech Lesniak

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology, Technology Classifications, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Research Tools > Imaging

Automatic Radiological Reports and ASPECTS Calculation from Brain MRIs

Unmet NeedThe typical workflow for reporting quantitative data in Picture Archive and Communication System (PACS), is redundant, subjective, time-consuming, and hard to record. Automated radiological reports describing consistent lesion features such as location, contrast, and volumes, and related effects is a time-saver, particularly in acute conditions...

Published: 3/14/2025 | Inventor(s): Andreia Faria, Chin-Fu Liu

Keywords(s):

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging

Myelin Protein Zero (MPZ)-targeting Compounds and Uses Thereof

Unmet NeedPeripheral nerve injuries require optimally timed intervention to maximize functional recovery and minimize permanent nerve death and negative impacts to quality of life. Current treatment plans rely primarily on monitoring for spontaneous healing or an indication that there must be surgical intervention, an approach that hinges on accurate...

Published: 3/14/2025 | Inventor(s): Martin Pomper, Catherine Foss, Sami Tuffaha, William Padovano, Bei Cheng

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology > Neuropathy, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Research Tools > Imaging

A Simplified and More Accessible Method for Production of 111In-XYIMSR for Patient Use

Unmet NeedEach year in the United States, ~82,000 patients are diagnosed with renal cell carcinoma (RCC), and there are ~15,000 RCC-related deaths (1). 75-85% of these cancers are subtyped as clear cell renal cell carcinoma (ccRCC) (2). ccRCC is characterized by overexpression of carbonic anhydrase IX (CAIX) (3). Researchers have previously developed...

Published: 3/14/2025 | Inventor(s): Martin Pomper, Babak Behnam Azad, Robert Dannals, Daniel Holt

Keywords(s):

Category(s): Clinical and Disease Specializations, Technology Classifications > Diagnostics > Diagnostic Imaging, Clinical and Disease Specializations > Oncology > Renal Cell Carcinoma

Compact Capillaroscope for Non-invasive Blood Analysis

Unmet NeedAnalysis of a complete blood count (CBC) test can help detect a plethora of diseases and conditions including leukemia, anemia, and blood infections. The information gained from a CBC analysis helps doctors treat any unusual symptoms, reduce risk of disease or complications, or simply help the patient make decisions to optimize their health....

Published: 3/14/2025 | Inventor(s): Nicholas Durr, Gregory McKay

Keywords(s):

Category(s): Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Diagnostics > In Vivo Diagnostics, Clinical and Disease Specializations > Hematology, Technology Classifications > Medical Devices > Imaging

Neuroscore

NeuroscoreJHU Ref #: C17050Technology Description: Researchers at Johns Hopkins University have developed a product that provides a uniform clinical score for Sturge-Weber Syndrome by determining whether cortical atrophy correlates to clinical severity. The clinical severity was evaluated using computer aided analysis of MRIs to produce laterality scores...

Published: 3/14/2025 | Inventor(s): Anne Comi

Keywords(s):

Category(s): Technology Classifications > Diagnostics > Diagnostic Imaging, Clinical and Disease Specializations > Neurology, Express Licensing

Thymosin-based Peptides for Non-invasive Cancer Detection and Targeted Delivery

Unmet Need:Breast cancer is the second most common cancer among women in the US. In 2017, for every 100,000 women, 125 new Female Breast Cancer cases were reported and 20 women died of breast cancer (see CDC, 2020). Currently, mammography is the primary screening approach for breast cancer with limitations such as occult disease as well as breast tissue...

Published: 3/14/2025 | Inventor(s): Babak Behnam Azad

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology > Breast Cancer, Technology Classifications > Diagnostics > Diagnostic Imaging

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