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Devices and Methods for Active Surveillance of Shunt-implanted Patients

Value Proposition· Continuous Monitoring: Researchers at Johns Hopkins have developed a self-monitoring shunt device that continuously monitors white blood cell (WBC) count and cerebrospinal fluid (CSF) flow. · Early Detection: This technology enhances the monitoring of patients with shunt implants by continuously detecting particulate matter—such...

Published: 6/27/2025 | Inventor(s): Jeeun Kang, Joseph Dardick, Mark Luciano, Emad Boctor

Keywords(s):

Category(s): Technology Classifications > Diagnostics > Precision Medicine Tools, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Neurostimulation

Natural Language Interface for Robotic C-arm X-ray Systems

Value Proposition· Ease of Use – clinicians can operate the device hands-free.· Enhanced Efficiency – voice commands reduce the time needed to position the C-arm and improving overall imaging efficiency.· Accessibility – this technology can make the equipment more accessible to users who may have difficulty with traditional joystick...

Published: 6/27/2025 | Inventor(s): Mathias Unberath, Benjamin Killeen

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Diagnostics > Diagnostic Imaging

Combined mammography and quantitative ultrasound breast imaging system

Value Proposition· Comprehensive Examination – integrates conventional ultrasound, ultrasound tomography, photoacoustic imaging, and mammography.· Superior Accuracy – multiple imaging modalities deliver comprehensive and precise breast tissue analysis, reducing the risk of overdiagnosis and/or overtreatment. · Improved Early Detection...

Published: 6/27/2025 | Inventor(s): Emad Boctor, Yixuan Wu, Jeeun Kang, Keshuai Xu, Hyunwoo Song, Russell Taylor, Yuxin Chen, Yifan Yin, Joseph Stayman, Mohammad Salehizadeh

Keywords(s):

Category(s): Technology Classifications, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology > Breast Cancer, Clinical and Disease Specializations > Women's Health

Apparatus and Method for modular ultrasound and photoacoustic imaging and interactive guidance using a position-tracked modular imaging framework

Value Proposition· Wearable ultrasound system that is adaptable to different patient physiologies and ages.· Allows for longitudinal and non-invasive monitoring of internal organs of critical care patients.· Applicable across a broad range of organ systems and disease indications.· Simulation-aided interactive guidance simplifies...

Published: 6/27/2025 | Inventor(s): Jeeun Kang, Emad Boctor, Ananya Tandri

Keywords(s):

Category(s): Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Imaging

Non-contact Ultrasound Tomography Imaging System

Multifunctional 3D ultrasound imaging systemJHU Ref #: C17859Value Proposition:· Generation of high resolution 3D images for detection and diagnosis of diseases.· Overcomes previous required use of media (water) to image.· Media-less imaging ability allows for integration of other imaging techniques (MRI, PET, CT). Unmet Need· The...

Published: 6/27/2025 | Inventor(s): Jeeun Kang, Emad Boctor, Hyunwoo Song, Yixuan Wu

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Breast Cancer, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging

Imaging Mannose Overexpression for Grading Glioblastoma Aggressiveness

Value Proposition:Label-free MRI method that requires no regulatory approval or additional drug developmentCan significantly decrease the time between initial diagnosis and follow-up treatment, as tumor aggressiveness could be predicted during the initial diagnostic MRI, improving patient survival rates and post-treatment evaluationNon-invasive diagnostic...

Published: 6/27/2025 | Inventor(s): Jeff Bulte, Behnaz Ghaemi

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology > Brain Cancer, Clinical and Disease Specializations > Oncology > Glioblastoma, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Diagnostics > Prognostic Biomarkers, Technology Classifications > Research Tools > Imaging

18F-Labeled PET Radiotracers for Imaging Neuroinflammation in the Brain

Value Proposition:· Quantification and PET imaging of microglial cells in the brain· Diagnostic for neuroinflammatory disorders – Alzheimer’s and MS· Favorable compound half-life enables shipping· Potential for non-CNS applications Technology DescriptionResearchers at Johns Hopkins have developed a series of Positron Emission Tomography...

Published: 6/27/2025 | Inventor(s): Martin Pomper, Deepankar Das, Andrew Horti, Wojciech Lesniak

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology, Technology Classifications, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Research Tools > Imaging

Automatic Radiological Reports and ASPECTS Calculation from Brain MRIs

Unmet NeedThe typical workflow for reporting quantitative data in Picture Archive and Communication System (PACS), is redundant, subjective, time-consuming, and hard to record. Automated radiological reports describing consistent lesion features such as location, contrast, and volumes, and related effects is a time-saver, particularly in acute conditions...

Published: 6/27/2025 | Inventor(s): Andreia Faria, Chin-Fu Liu

Keywords(s):

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging

Myelin Protein Zero (MPZ)-targeting Compounds and Uses Thereof

Unmet NeedPeripheral nerve injuries require optimally timed intervention to maximize functional recovery and minimize permanent nerve death and negative impacts to quality of life. Current treatment plans rely primarily on monitoring for spontaneous healing or an indication that there must be surgical intervention, an approach that hinges on accurate...

Published: 6/27/2025 | Inventor(s): Martin Pomper, Catherine Foss, Sami Tuffaha, William Padovano, Bei Cheng

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology > Neuropathy, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Research Tools > Imaging

A Simplified and More Accessible Method for Production of 111In-XYIMSR for Patient Use

Unmet NeedEach year in the United States, ~82,000 patients are diagnosed with renal cell carcinoma (RCC), and there are ~15,000 RCC-related deaths (1). 75-85% of these cancers are subtyped as clear cell renal cell carcinoma (ccRCC) (2). ccRCC is characterized by overexpression of carbonic anhydrase IX (CAIX) (3). Researchers have previously developed...

Published: 6/27/2025 | Inventor(s): Martin Pomper, Babak Behnam Azad, Robert Dannals, Daniel Holt

Keywords(s):

Category(s): Clinical and Disease Specializations, Technology Classifications > Diagnostics > Diagnostic Imaging, Clinical and Disease Specializations > Oncology > Renal Cell Carcinoma

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