Search Results - jeff+bulte

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All-in-one Multimodal Nanotheranostic Platform for Image-Guided Therapy

Unmet NeedWith 30 million magnetic resonance imaging (MRI) scans (Envision Radiology) and 80 million computed tomography (CT) scans each year in the United States alone (Harvard Health), medical imaging has become a powerful tool for doctors to diagnose and treat illnesses and injuries ranging from cancer to respiratory diseases. However, each modality...

Published: 6/28/2024 | Inventor(s): Jeff Bulte, Ali Shakeri-Zadeh, Chao Wang

Keywords(s):

Category(s): Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging, Clinical and Disease Specializations > Oncology

Novel CEST MRI-suitable Reporter Genes to Non-Invasively Monitor Distribution and Migration of Biotherapeutics

Unmet NeedGreen Fluorescent Protein (GFP) reporter genes and PET (positron-emission tomography) imagining are two techniques which have been widely used to monitor the movement and distribution of specific molecules in cells or animals. Imaging GFP-tagged molecules is often destructive to the sample and is limited by the degree that light can penetrate...

Published: 6/27/2024 | Inventor(s): Assaf Gilad, Michael Mcmahon, Paul Winnard, Venu Raman, Jeff Bulte, Peter van Zijl

Keywords(s): Imaging Agent, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Magnetic Resonance Imaging (MRI)

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices

Non-invasive Sensing of Free Metal Ions Using iCEST

C12425: MRI-based Non-Invasive Metal Ion Detection SystemNovelty: Novel method combining chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) with 19F fluorinated chelators to detect free metal ions with high sensitivity and specificity.Value Proposition: Although metal ions are involved in a myriad of biological processes,...

Published: 6/27/2024 | Inventor(s): Michael Mcmahon, Jeff Bulte, Amnon Bar-Shir

Keywords(s): Chemical particulates, Environmental Sensing, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Integrated Sensing System, Magnetic Resonance Imaging (MRI), Sensing Modality

Category(s): Technology Classifications > Computers, Electronics & Software > Sensors, Technology Classifications > Industrial Tech > Energy, Infrastructure & Environment, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Industrial Tech, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Engineering Tech > Energy, Infrastructure & Environment

CEST Substrates

C12412: New Reporter System for CEST MRINovelty: Novel reporter system for chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) without paramagnetic metal substrates.Value Proposition: Among the clinically applied 3D imaging modalities, MRI has the highest resolution and is therefore the preferred method for detection of cellular...

Published: 6/27/2024 | Inventor(s): Jeff Bulte, Guanshu Liu, Raag Airan, Michael Mcmahon, Peter van Zijl, Amnon Bar-Shir, Assaf Gilad

Keywords(s): Imaging Agent, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Magnetic Resonance Imaging (MRI)

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices, Technology Classifications > Computers, Electronics & Software > Sensors

Length (and Offset) VARied Saturation (LOVARS) Method for Chemical Exchange Saturation Transfer (CEST) MRI

C11505: Method for Obtaining Multi-probe Magnetic Resonance Images (MRI)Novelty: A novel method of obtaining simultaneous detection of multiple probes within an MRI, allowing for a visual representation of the data that can be separated based on probes.Value Proposition: Current MRI technology would significantly benefit from having the ability to discriminate...

Published: 6/27/2024 | Inventor(s): Jeff Bulte, Assaf Gilad, Michael Mcmahon, Xiaolei Song

Keywords(s): Cancers, Disease Indication, Image Processing Software, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Magnetic Resonance Imaging (MRI)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices