Search Results - paul+winnard

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Novel CEST MRI-suitable Reporter Genes to Non-Invasively Monitor Distribution and Migration of Biotherapeutics

Unmet NeedGreen Fluorescent Protein (GFP) reporter genes and PET (positron-emission tomography) imagining are two techniques which have been widely used to monitor the movement and distribution of specific molecules in cells or animals. Imaging GFP-tagged molecules is often destructive to the sample and is limited by the degree that light can penetrate...

Published: 6/27/2024 | Inventor(s): Assaf Gilad, Michael Mcmahon, Paul Winnard, Venu Raman, Jeff Bulte, Peter van Zijl

Keywords(s): Imaging Agent, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Magnetic Resonance Imaging (MRI)

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices

Unique Organ-specific Metastatic Human Breast Cancer Cell Lines

TITLEUnique organ-specific metastatic human breast cancer cell lines CASE NUMBERC13010 ABSTRACTA history of clinical observations has demonstrated that breast cancer metastases are capable of sustained deadly growth in several vital organs, such as, lung, brain, and liver as well as bone/marrow, ovaries, adrenals, lymph nodes, and skin. In order to...

Published: 6/27/2024 | Inventor(s): Venu Raman, Paul Winnard

Keywords(s): Breast Cancer, Cancer Cells, Cancers, Cell Lines, Cell Model, Discovery/Research Tools, Disease Indication, Human Cell Lines, In Vitro Research Tool, Translational Research Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Breast Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools

Clinically Relevant Tissue Specific Fluorescent Metastatic Human Breast Cancer Cell Lines

C10939: Clinically Relevant Tissue Specific Fluorescent Metastatic Human Breast Cancer Cell LinesValue Proposition: • Overcomes several inherent shortcomings of present breast cancer xenograft model systems. • Provides definitive clinical models of human breast cancer in mice that are comparable to the human disease by accurately recapitulating...

Published: 6/27/2024 | Inventor(s): Mahendran Botlagunta, Paul Winnard, Venu Raman

Keywords(s): Basic Research Biomarker, Breast Cancer, Cancer Cells, Cancers, Cell Lines, Cell Model, Discovery/Research Tools, Disease Indication, Human Cell Lines, In Vitro Research Tool, Labels/Markers, Research Reagent

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Breast Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology

Novel Breast Cancer Cells That Stably Express a New Orange-red Fluorescent Protein Provides Facile Tracking of Metastatic Progression In Live Animal Model Systems

C05061: Novel Breast Cancer Cells That Stably Express a New Orange-red Fluorescent Protein Provides Facile Tracking of Metastatic Progression In Live Animal Model Systems Technical Details: Modeling human disease states in mice has a profound impact on our understanding of disease progression and treatment development. The need for noninvasive longitudinal...

Published: 6/27/2024 | Inventor(s): Paul Winnard, Venu Raman

Keywords(s): Basic Research Biomarker, Breast Cancer, Cancers, Cell Lines, Discovery/Research Tools, Disease Indication, Human Cell Lines, In Vitro Research Tool, Labels/Markers, Research Reagent, Translational Research Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Breast Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools > Human Cell Lines