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Polymer-based Acriflavine Wafers for the Treatment of Malignant Brain Cancer

Value Proposition:· Intracranial wafers deliver anti-cancer drugs directly to the tumor, circumventing pharmacokinetic barriers.· Repurposes acriflavine and polymers, both with other FDA approvals, for malignant glioma.· High-efficacy treatment option to prolong survival for the most common form of aggressive brain cancer.· 10-fold...

Published: 3/13/2025 | Inventor(s): Betty Tyler, Antonella Mangraviti, Henry Brem, Alessandro Olivi, Tula Raghavan

Keywords(s): Brain Cancer, Cancers, Disease Indication, Drug Delivery Mechanism, Drug Delivery Vehicle, Glioma, Non-novel, Polymers, Predicted Novelty, Repurposed, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Oncology > Brain Cancer, Clinical and Disease Specializations > Oncology > Glioma, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities