Search Results - betty+tyler

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Value PropositionEnhanced effect of immunotherapyTreatment for recurrent or metastatic diseaseImproved glioma treatment Unmet NeedImmunotherapy represents a new paradigm in cancer treatment. Molecules that effectively reverse the immune suppressing nature of cancer have the potential to enhance the body’s ability to work systemically combat cancer (Pardoll,...

Published: 3/12/2026 | Inventor(s): Dimitrios Mathios, Betty Tyler, Drew Pardoll, Henry Brem, Michael Lim

Keywords(s): Antagonists/Inhibitors, Cancers, Chemotherapy/Immunotherapy, Combination, Disease Indication, Non-novel, Predicted Novelty, Repurposed, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Immunology, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities

Polymer-based Acriflavine Wafers for the Treatment of Malignant Brain Cancer

Value Proposition:· Intracranial wafers deliver anti-cancer drugs directly to the tumor, circumventing pharmacokinetic barriers.· Repurposes acriflavine and polymers, both with other FDA approvals, for malignant glioma.· High-efficacy treatment option to prolong survival for the most common form of aggressive brain cancer.· 10-fold...

Published: 3/12/2026 | Inventor(s): Betty Tyler, Antonella Mangraviti, Henry Brem, Alessandro Olivi, Tula Raghavan

Keywords(s): Brain Cancer, Cancers, Disease Indication, Drug Delivery Mechanism, Drug Delivery Vehicle, Glioma, Non-novel, Polymers, Predicted Novelty, Repurposed, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Oncology > Brain Cancer, Clinical and Disease Specializations > Oncology > Glioma, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities

Intraoperatively Placed Markers for Post-surgical Imaging

Invention Novelty: A dissolvable polymer implant impregnated with contrast agent to improve anchoring with minimal tissue displacement.Value Proposition:The main limitation of current neuronavigation systems is that they rely on preoperative images for accurate navigation. The brain is susceptible to a phenomenon called brainshift due to CSF leakage...

Published: 3/12/2026 | Inventor(s): Sheng-fu Lo, Jason Liauw, Betty Tyler, Henry Brem, Michael Lim

Keywords(s): Imaging Agent, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Magnetic Resonance Imaging (MRI)

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices