Search Results - michael+lim

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Modulation of Oxidative Stress as a Therapeutic Pathway in Trigeminal Neuralgia

Unmet NeedTrigeminal neuralgia is a condition that affects the fifth cranial nerve, caused either via trigeminal nerve compression or secondary to another medical condition (i.e., multiple sclerosis, facial injury, tumors, etc.). Trigeminal neuralgia results in severe orofacial pain that is exceptionally debilitating, with a profound effect on one’s...

Published: 3/14/2025 | Inventor(s): Michael Lim, Solomon Snyder, Risheng Xu, Chirag Vasavda, Ryan Dhindsa

Keywords(s):

Category(s): Clinical and Disease Specializations, Technology Classifications, Technology Classifications > Therapeutic Modalities > Small Molecules

Intraoperatively Placed Markers for Post-surgical Imaging

Invention Novelty: A dissolvable polymer implant impregnated with contrast agent to improve anchoring with minimal tissue displacement.Value Proposition:The main limitation of current neuronavigation systems is that they rely on preoperative images for accurate navigation. The brain is susceptible to a phenomenon called brainshift due to CSF leakage...

Published: 3/13/2025 | Inventor(s): Sheng-fu Lo, Jason Liauw, Betty Tyler, Henry Brem, Michael Lim

Keywords(s): Imaging Agent, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Magnetic Resonance Imaging (MRI)

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices

Glioblastoma Biomarker for Improved Survival Prediction

TITLE: Glioblastoma Biomarker for Improved Survival PredictionCASE NUMBER: C13155UNMET NEEDGlioblastoma GBM), the most common primary brain tumor, has few available therapies providing significant improvement in survival. The median survival of patients after treatment is ~15 months, with only 3-5% surviving longer than 3 years. However, survival varies...

Published: 3/13/2025 | Inventor(s): Patrick Ha, Michael Lim, Chetan Bettegowda, Taeyoung Hwang, Chul-Kee Park, Dimitrios Mathios

Keywords(s): Biomarker, Brain Cancer, Breast Cancer, Cancers, Cervical Cancer, Clinical Diagnostics, Disease Indication, Glioma, In Vitro Diagnostics, Lung Cancer, Prognostic Biomarker

C11601: Novel Adjuvant Based Approach to Enhance Cancer Immunotherapy

Novelty: This invention is a novel means of augmenting immune-based cancer therapies by using a physical intervention to counter a tumor's natural immunosuppressive effect.Value Proposition: This therapeutic strategy combines two accepted approaches to cancer management - immune-based and physical - for an increase in survival that is durable and significantly...

Published: 3/13/2025 | Inventor(s): Charles Drake, Drew Pardoll, Jing Zeng, Michael Lim

Keywords(s): Cancers, Combination, Disease Indication, External Beam Radiation, Immunotherapy/Radiation therapy, Interventional and Surgical Systems, Surgical Intervention Method, Therapeutic Matter, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Medical Devices, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities