Search Results - xuhang+li

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Multi-atlas Library of Brain Gray Matter Nuclei in Susceptibility MRI

Unmet NeedDespite the extensive research on the anatomy of the human brain, there still remains many anatomical features that are difficult to characterize. Additionally, anatomical brain variation amongst individuals participating in research may contribute toward ambiguity in understanding specific structures of the brain. The brain is composed of...

Published: 7/5/2024 | Inventor(s): Andreia Faria, Xu Li

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Databases, Technology Classifications > Research Tools > Imaging, Clinical and Disease Specializations > Neurology

Treatment of Injury or Neurodegenerative Disorders of the Enteric Nervous System (ENS) that cause Gastrointestinal Dysfunctions for which There is No Effective Therapy

JHU Ref. C13755Title: Preconditioned BMSC Promote de novo Nerve Regeneration: Potential application in therapy of enteric nerve injury/disorders and vascularized composite allotransplantation (VCA) UNMET NEEDInjury or neurodegenerative disorders of the enteric nervous system (ENS) cause gastrointestinal dysfunctions for which there is no effective therapy,...

Published: 7/4/2024 | Inventor(s): Xuhang Li, Xiaohua Hou, Rong Lin

Keywords(s): Cell Therapy, Disease Indication, Gastrointestinal Disorders, Single, Therapeutic Matter, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology, Technology Classifications > Therapeutic Modalities > Cell Therapies, Technology Classifications > Therapeutic Modalities

Inflammatory Bowel Disease (IBD): New Cytokine Biomarkers

C10931: Markers for Diagnosis and/or Prognosis of Irritable Bowel Disease and Syndrome Value Proposition: - The identified markers may be combined to optimize sensitivity and specificity. - These markers may be used in ELISA or Chip format. - Markers have been validated using colonic tissue biopsy samples. - Predicate technology and CPT codes already...

Published: 7/4/2024 | Inventor(s): Michael Centola, Nicholas Knowlton, Xuhang Li, Philip Alex

Keywords(s): Biomarker, Chronic Inflammatory Diseases, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, Gastrointestinal Disorders, In Vitro Diagnostics, Inflammatory Bowel Disease, Inflammatory Bowel Disease (IBD)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology > Inflammatory Bowel Disease, Clinical and Disease Specializations > Inflammation > Chronic Inflammatory Diseases, Clinical and Disease Specializations > Rare Diseases, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Inflammation

Identification of Novel Serological Biomarkers for Inflammatory Bowel Disease Using E.coli Proteome Chip

C10584: Novel Diagnostics for IBDNovelty: This technology involves use of novel E. coli proteome chip to diagnose, monitor and select appropriate treatments for patients suffering from inflammatory bowel disease (IBD).Value Proposition: Current diagnostic methods for inflammatory bowel disease are invasive and patients find these tests unpleasant. The...

Published: 7/4/2024 | Inventor(s): Heng Zhu, Xuhang Li

PNU-120596 and 3-(2,4-dimethoxybenzylidene) Anabaseine (GTS-21) (both nAchRa7 agonists) and Methyllycaconitine (anAchRa7 antagonist), are Highly Effective Drugs in Therapy of Ulcerative Colitis (UC) and Crohn's Disease (CD)

C10382: Breakthrough Therapeutic for Inflammatory Bowel Diseases (IBD)Novelty: This technology identifies a nicotinic acetylcholine receptor isoform (nAChR7) that has a prevalent role in affecting Inflammatory Bowel Disease (IBD), as well as several agonist/antagonists to nAChR7, that are highly effective in both the prevention and therapy of ulcerative...

Published: 7/4/2024 | Inventor(s): Philip Alex, Michael Centola, Xuhang Li

Keywords(s): Chronic Inflammatory Diseases, Combination, Crohn's disease, Crohn's Disease, Disease Indication, Gastrointestinal Disorders, Inflammatory Bowel Disease, Inflammatory Bowel Disease (IBD), Natural compounds, Non-novel, Off-the-shelf, Predicted Novelty, Small Molecules, Targeted Therapy/Targeted Therapy, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Ulcerative Colitis, Ulcerative Colitis (UC)