Search Results - andrew+cheetham

2 Results

Sort By:

Selective Targeting of a Novel Protective Anti-inflammatory Receptor in Human Mitochondria and its Role in Preserving Mitochondrial Functions

Unmet NeedAccording to WHO, over one billion people worldwide are living with elevated blood pressure which may lead to a range of adverse health conditions that cause ~1,100 deaths per day. Many current high blood pressure therapies focus on angiotensin receptor blocking drugs. Unfortunately, adverse events (e.g., renal dysfunction, hyperkalemia, and...

Published: 5/9/2024 | Inventor(s): Andrew Cheetham, Peter Abadir, Jeremy Walston, Honggang Cui

Keywords(s): Antagonists/Inhibitors, Novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities

Self-Assembling Drug-Amphiphiles: A New Platform for the Delivery of Anticancer Chemotherapeutics

UNMET NEEDMany anticancer drug delivery systems suffer from lack of target specificity and drug-loading limitations. Additionally, many drug delivery systems require the use of a nanocarrier, which have certain disadvantages including limitations on the amount of loaded drug and batch to batch variability. This invention is a self-assembled drug-amphiphile...

Published: 5/9/2024 | Inventor(s): Andrew Cheetham, Pengcheng Zhang, Honggang Cui

Keywords(s): Cancers, Chemotherapy, Disease Indication, Drug Delivery Vehicle, Peptides/Prodrugs, Single, Therapeutic Matter, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Peptides, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities