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C13826: Quantitative Determination of Nucleoside Analogue Drugs in Genomic DNA or RNA

Unmet Need:Hematologic and epithelial malignancies have been shown to progress by epigenetically silencing genes that code for tumor suppressors, cell cycle regulators or proteins involved in cell-cell interaction. Gene suppression occurs through promoter methylation and modification of histones. Drugs which are able to manipulate promoter methylation...

Published: 6/13/2024 | Inventor(s): Michelle Rudek-Renaut, Srinivasan Yegnasubramanian, Nicole Anders

Keywords(s): Analytical Method, Assay, Biomarker, Cancers, Clinical Diagnostics, Discovery/Research Tools, Disease Indication, Epigenetic, In Vitro Diagnostics, In Vitro Research Tool, Methylation

Category(s): Technology Classifications > Research Tools, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools > Assays