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This invention describes a method for creating novel, inhibitors of desired bacterial rhomboid proteases (RhP), and applies this method to produce potent antibiotics. The value proposition is very high providing a means of identifying and creating novel, specific bacterial Rhp inhibitors (antibiotics) with a novel mechanism of action to prevent/overcome...

Published: 5/9/2024 | Inventor(s): Sinisa Urban, Shiv Gandhi, Sangwoo Cho

Keywords(s): Antagonists/Inhibitors, Bacterial Infections, Biologics, Disease Indication, Infectious Diseases, Malaria, Parasitic Infections, Peptide, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Malaria, Clinical and Disease Specializations > Infectious Diseases > Parasitic Infections, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Peptides, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Technology Classifications > Therapeutic Modalities > Small Molecules