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A Transgenic Mouse Model of Atopic Dermatitis, Skin Remodeling, and Atopic March

Value Proposition:JHU scientists have developed an inducible transgenic model in which IL-13 can be expressed in the skin to define the resulting dermal and systemic phenotypes and mechanisms involved. The mice display increased susceptibilty to allergen stimulation in the airways even though the original pathology is in the skin.- Published as: Zheng...

Published: 6/27/2024 | Inventor(s): Zhou Zhu, Tao Zheng

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, In Vivo Research Tool, Mouse Model, Mouse Model Xenograft, Skin Disorders, Target-based Screening Tool

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools, Clinical and Disease Specializations > Dermatology > Atopic Dermatitis, Clinical and Disease Specializations > Dermatology