Search Results - clinical+and+disease+specializations+%3e+gastroenterology+%3e+inflammatory+bowel+disease

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Value Proposition· Autoantibody that promotes DNA degradation to diminish inflammation· Enhances endonuclease DNase1L3 activity· Avoids kidney-mediated inflammatory response Unmet Need· Extracellular DNA, also called cell-free DNA, released from dying cells or activated immune cells can be recognized by the immune system...

Published: 3/14/2025 | Inventor(s): Felipe Andrade, Jose de Jesus Eduardo Gomez-Bañuelos

Keywords(s):

Category(s): Clinical and Disease Specializations > Genetic Diseases > Cystic Fibrosis, Clinical and Disease Specializations > Gastroenterology > Inflammatory Bowel Disease, Technology Classifications > Therapeutic Modalities > Antibodies, Technology Classifications > Therapeutic Modalities > Therapeutic Antibodies, Clinical and Disease Specializations > Inflammation > Arthritis

Nanoparticle-NHE3 Peptide to Treat Diarrhea

Value Proposition:· Nanoparticle-based delivery of therapeutic that enhances intestinal sodium absorption · Broad clinical applications in severe diarrhea, whether acute or chronic· Effective treatment across heterogeneous presentations of diarrhea · Appropriate for patients of all ages Technology Description· Researchers...

Published: 3/14/2025 | Inventor(s): Mark Donowitz, Jordan Green, Nicholas Zachos, Hannah Vaughan

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Inflammatory Bowel Disease (IBD): New Cytokine Biomarkers

C10931: Markers for Diagnosis and/or Prognosis of Irritable Bowel Disease and Syndrome Value Proposition: - The identified markers may be combined to optimize sensitivity and specificity. - These markers may be used in ELISA or Chip format. - Markers have been validated using colonic tissue biopsy samples. - Predicate technology and CPT codes already...

Published: 3/13/2025 | Inventor(s): Michael Centola, Nicholas Knowlton, Xuhang Li, Philip Alex

Keywords(s): Biomarker, Chronic Inflammatory Diseases, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, Gastrointestinal Disorders, In Vitro Diagnostics, Inflammatory Bowel Disease, Inflammatory Bowel Disease (IBD)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Gastroenterology > Inflammatory Bowel Disease, Clinical and Disease Specializations > Inflammation > Chronic Inflammatory Diseases, Clinical and Disease Specializations > Rare Diseases, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Gastroenterology, Clinical and Disease Specializations > Inflammation

Identification of Novel Serological Biomarkers for Inflammatory Bowel Disease Using E.coli Proteome Chip

C10584: Novel Diagnostics for IBDNovelty: This technology involves use of novel E. coli proteome chip to diagnose, monitor and select appropriate treatments for patients suffering from inflammatory bowel disease (IBD).Value Proposition: Current diagnostic methods for inflammatory bowel disease are invasive and patients find these tests unpleasant. The...

Published: 3/13/2025 | Inventor(s): Heng Zhu, Xuhang Li

PNU-120596 and 3-(2,4-dimethoxybenzylidene) Anabaseine (GTS-21) (both nAchRa7 agonists) and Methyllycaconitine (anAchRa7 antagonist), are Highly Effective Drugs in Therapy of Ulcerative Colitis (UC) and Crohn's Disease (CD)

C10382: Breakthrough Therapeutic for Inflammatory Bowel Diseases (IBD)Novelty: This technology identifies a nicotinic acetylcholine receptor isoform (nAChR7) that has a prevalent role in affecting Inflammatory Bowel Disease (IBD), as well as several agonist/antagonists to nAChR7, that are highly effective in both the prevention and therapy of ulcerative...

Published: 3/13/2025 | Inventor(s): Philip Alex, Michael Centola, Xuhang Li

Keywords(s): Chronic Inflammatory Diseases, Combination, Crohn's disease, Crohn's Disease, Disease Indication, Gastrointestinal Disorders, Inflammatory Bowel Disease, Inflammatory Bowel Disease (IBD), Natural compounds, Non-novel, Off-the-shelf, Predicted Novelty, Small Molecules, Targeted Therapy/Targeted Therapy, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Ulcerative Colitis, Ulcerative Colitis (UC)