Search Results - clinical+and+disease+specializations+%3e+psychiatry+%3e+suicidal+impulses

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Mechanistic insights reveal drug discovery target for lithium responders and non-responders

Value PropositionNew mouse model for mood switching behavior with viability for compound screeningDemonstrated that BK channels in excitatory neurons are involved in cellular pathology of patients by affecting Ca2+ kineticsApplication to both lithium responders and non-responders Unmet NeedBipolar disorder (BPD) has a lifetime prevalence of 4-5% in...

Published: 3/14/2025 | Inventor(s): Akira Sawa, Rupali Srivastava, Koko Ishizuka

Keywords(s):

Category(s): Clinical and Disease Specializations > Psychiatry > Bipolar Disorder, Clinical and Disease Specializations > Psychiatry > Mood Disorders, Clinical and Disease Specializations > Psychiatry > Suicidal Impulses, Technology Classifications > Research Tools > Animal Models

A DNA methylation and genotype specific biomarker of suicide attempt

Novel Biomarkers for Predicting Suicide RiskJHU REF: [C12394]Invention Novelty: This invention provides DNA methylation-based biomarkers for predicting suicide risk. Value Proposition: Almost 30,000 people die of suicide each year in the United States, and 1 million people die worldwide. In the teenage population, it is the second leading cause of...

Published: 3/13/2025 | Inventor(s): Holly Wilcox, Zachary Kaminsky

Keywords(s): Biomarker, Clinical Diagnostics, CNS and Neurological Disorders, Disease Indication, Epigenetic, In Vitro Diagnostics, In Vitro Diagnostics (Old), Methylation, Prognostic Biomarker, Psychiatric Diseases, Suicidal Impulses, Suicide/Suicidal Impulses

Category(s): Clinical and Disease Specializations, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > Prognostics Biomarkers, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Psychiatry, Clinical and Disease Specializations > Psychiatry > Suicidal Impulses