Search Results - rupali+srivastava

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Mechanistic insights reveal drug discovery target for lithium responders and non-responders

Value PropositionNew mouse model for mood switching behavior with viability for compound screeningDemonstrated that BK channels in excitatory neurons are involved in cellular pathology of patients by affecting Ca2+ kineticsApplication to both lithium responders and non-responders Unmet NeedBipolar disorder (BPD) has a lifetime prevalence of 4-5% in...

Published: 3/14/2025 | Inventor(s): Akira Sawa, Rupali Srivastava, Koko Ishizuka

Keywords(s):

Category(s): Clinical and Disease Specializations > Psychiatry > Bipolar Disorder, Clinical and Disease Specializations > Psychiatry > Mood Disorders, Clinical and Disease Specializations > Psychiatry > Suicidal Impulses, Technology Classifications > Research Tools > Animal Models

Johns Hopkins University PROTEIN-DB2 Database System

C04853: Johns Hopkins University PROTEIN-DB2 Database SystemNovelty: The current invention is a relational database for proteomic experiments.Value Proposition: Proteomic data collection follows complex workflow, ranging from gel electrophoresis to mass spectrometry to liquid chromatography or a combination thereof. In addition, amplification of low-abundance...

Published: 3/13/2025 | Inventor(s): Raimond Winslow, Stephen Granite, Chunguang Yang, Ali Ali, Donita Robinson

Keywords(s): Computer and Network Systems, Computer Software, Computing; Calculating; Counting, Data Processing Systems or Methods, Specifically Adapted fo~, Data Processing Systems or Methods, Specifically Adapted for, Physics

Category(s): Technology Classifications > Computers, Electronics & Software > Financial Tech, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Databases