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Development of New Monoclonal Antibodies Recognizing Human Prostate-specific Membrane Antigen (PSMA)

Unmet Need Prostate-specific membrane antigen (PSMA, also known as GCPII) is a validated target for prostate cancer imaging and therapy. Macromolecular reagents, most notably monoclonal antibodies (mAbs), offer a viable alternative to small-molecule PSMA ligands for imaging and therapy. However existing anti-PSMA antibodies have several drawbacks, including...

Published: 3/13/2025 | Inventor(s): Martin Pomper, Catherine Foss, Cyril Barinka, Zora Novakova

Keywords(s): Antibodies, Biologics, Cancers, Disease Indication, Imaging Agent, Imaging and Sensing Systems, In Vivo Medical Imaging, Prostate Cancer, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Men's Health, Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Therapeutic Modalities > Antibodies, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities