Search Results - catherine+foss

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Uses of PSMA- and TSPO-targeting Compounds for Evaluation of Injuries in the Peripheral Nervous System

Value Proposition:· Technology combines positron emission tomography (PET) with targeted imaging compounds for a first-in-class approach to peripheral nerve injury (PNI) evaluation and monitoring.· Provides a method for non-invasive evaluation of PNI status immediately post-injury and over the recovery timeline. · Implementation...

Published: 9/27/2024 | Inventor(s): Martin Pomper, Catherine Foss, Sami Tuffaha, William Padovano

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Myelin Protein Zero (MPZ)-targeting Compounds and Uses Thereof

Unmet NeedPeripheral nerve injuries require optimally timed intervention to maximize functional recovery and minimize permanent nerve death and negative impacts to quality of life. Current treatment plans rely primarily on monitoring for spontaneous healing or an indication that there must be surgical intervention, an approach that hinges on accurate...

Published: 9/27/2024 | Inventor(s): Martin Pomper, Catherine Foss, Sami Tuffaha, William Padovano, Bei Cheng

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Category(s): Clinical and Disease Specializations > Neurology > Neuropathy, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Research Tools > Imaging

PSMA-Targeted PAMAM Dendrimers for Specific Delivery of Imaging, Contrast and Therapeutic Agents

Unmet NeedAccording to The American Cancer Society, approximately 1 in 9 men will be diagnosed with prostate cancer in their lifetime, with 174,650 new cases diagnosed yearly in the US. As prostate cancer is the second leading cause of cancer death in American men, early detection is important for adequate treatment. The most common method of detecting...

Published: 9/26/2024 | Inventor(s): Martin Pomper, Wojciech Lesniak, Srikanth Boinapally, Sangeeta Ray, Catherine Foss

Keywords(s): Cancers, Dendrimers, Disease Indication, Drug Delivery Vehicle, Imaging Agent, Imaging and Sensing Systems, In Vivo Medical Imaging, Prostate Cancer, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Medical Devices > Imaging

Development of New Monoclonal Antibodies Recognizing Human Prostate-specific Membrane Antigen (PSMA)

Unmet Need Prostate-specific membrane antigen (PSMA, also known as GCPII) is a validated target for prostate cancer imaging and therapy. Macromolecular reagents, most notably monoclonal antibodies (mAbs), offer a viable alternative to small-molecule PSMA ligands for imaging and therapy. However existing anti-PSMA antibodies have several drawbacks, including...

Published: 9/26/2024 | Inventor(s): Martin Pomper, Catherine Foss, Cyril Barinka, Zora Novakova

Keywords(s): Antibodies, Biologics, Cancers, Disease Indication, Imaging Agent, Imaging and Sensing Systems, In Vivo Medical Imaging, Prostate Cancer, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Men's Health, Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Therapeutic Modalities > Antibodies, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities

Targeting Collagen Strands for Imaging and Therapy

C11749: Novel Collagen Targeting for Imaging and Therapeutic ApplicationsNovelty: This technology employs collagen mimetic peptides to target denatured collagen in vivo for imaging and treatment of cancer and other diseases affecting the collagen matrix.Value Proposition: There are currently no available means of targeting a denatured collagen matrix...

Published: 9/26/2024 | Inventor(s): Yang Li, Catherine Foss, Allen Yi-Lan Wang, Martin Pomper, Daniel Summerfield, Michael Yu

Keywords(s): Biologics, Cancers, Cardiovascular Diseases, Disease Indication, Imaging Agent, Imaging and Sensing Systems, In Vivo Medical Imaging, Peptide, Radioisotope Therapy, Therapeutic Matter, Therapeutic Substance, Therapeutics, Wound Healing

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Wound Healing, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Peptides, Technology Classifications > Medical Devices, Technology Classifications > Therapeutic Modalities