Search Results - radioisotope+therapy

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Alpha particle formulations for treatment of solid tumors

Unmet NeedHepatocellular carcinoma (HCC) is the fifth most common cancer type worldwide and a leading cause of cancer related deaths. HCC is clinically silent in its early stages, leading to diagnosis at more advanced stages when only non-surgical, palliative treatment is available. One treatment option for advanced HCC is intra-arterial therapy and...

Published: 3/14/2025 | Inventor(s): Jessie Nedrow, Eleni Liapi

Keywords(s): Biologics, Cancers, Disease Indication, Liver Cancer, Non-novel, Predicted Novelty, Radioisotope Therapy, Repurposed, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations > Oncology > Liver Cancer, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities > Repurposed Drugs

New fluorinated DREADD actuators and ligands suitable for PET imaging

Unmet NeedChemogenetics is defined as a method by which proteins are made to interact with small molecules, typically neurological molecules, as they have never been interacted with before. There is a powerful and versatile approach for remote and momentary manipulation of cellular activity called Designer Receptors Exclusively Activated by Designer...

Published: 3/14/2025 | Inventor(s): Andrew Horti, Martin Pomper, Michael Michaelides, Jordi Bonaventura, Feng Hu, Juan Luis Gomez, Marta Sanchez-Soto

Keywords(s): Biologics, Discovery/Research Tools, Imaging Agent, Imaging and Sensing Systems, In Vivo Medical Imaging, Labels/Markers, Radioisotope Therapy, Research Reagent, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Research Tools > Proteins, Ligands & Receptors

Targeting Collagen Strands for Imaging and Therapy

C11749: Novel Collagen Targeting for Imaging and Therapeutic ApplicationsNovelty: This technology employs collagen mimetic peptides to target denatured collagen in vivo for imaging and treatment of cancer and other diseases affecting the collagen matrix.Value Proposition: There are currently no available means of targeting a denatured collagen matrix...

Published: 3/13/2025 | Inventor(s): Yang Li, Catherine Foss, Allen Yi-Lan Wang, Martin Pomper, Daniel Summerfield, Michael Yu

Keywords(s): Biologics, Cancers, Cardiovascular Diseases, Disease Indication, Imaging Agent, Imaging and Sensing Systems, In Vivo Medical Imaging, Peptide, Radioisotope Therapy, Therapeutic Matter, Therapeutic Substance, Therapeutics, Wound Healing

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Wound Healing, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Peptides, Technology Classifications > Medical Devices, Technology Classifications > Therapeutic Modalities