Search Results - wojciech+lesniak

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18F-Labeled PET Radiotracers for Imaging Neuroinflammation in the Brain
Value Proposition:·      Quantification and PET imaging of microglial cells in the brain·      Diagnostic for neuroinflammatory disorders – Alzheimer’s and MS·      Favorable compound half-life enables shipping·      Potential for non-CNS applications Technology DescriptionResearchers at Johns Hopkins have developed a series of Positron Emission Tomography...
Published: 6/28/2024   |   Inventor(s): Martin Pomper, Deepankar Das, Andrew Horti, Wojciech Lesniak
Keywords(s):  
Category(s): Clinical and Disease Specializations > Neurology, Technology Classifications, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Research Tools > Imaging
PSMA-Targeted PAMAM Dendrimers for Specific Delivery of Imaging, Contrast and Therapeutic Agents
Unmet NeedAccording to The American Cancer Society, approximately 1 in 9 men will be diagnosed with prostate cancer in their lifetime, with 174,650 new cases diagnosed yearly in the US.  As prostate cancer is the second leading cause of cancer death in American men, early detection is important for adequate treatment.  The most common method of detecting...
Published: 6/27/2024   |   Inventor(s): Martin Pomper, Wojciech Lesniak, Srikanth Boinapally, Sangeeta Ray, Catherine Foss
Keywords(s): Cancers, Dendrimers, Disease Indication, Drug Delivery Vehicle, Imaging Agent, Imaging and Sensing Systems, In Vivo Medical Imaging, Prostate Cancer, Therapeutic Matter, Therapeutics
Category(s): Clinical and Disease Specializations > Oncology > Prostate Cancer, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Medical Devices > Imaging
Sialicylic Acid -Conjugated Dendrimers as a Tunable, High-Performance CEST MRI NanoPlatform for Diagnostic Imaging
Value Proposition: Brain tumors have poor survival rates and treatment options are limited due to the requirement of therapeutics to cross the blood-brain-barrier to reach the tumor site. Convection-enhanced delivery (CED) of nanoformulations is gaining increasing attention to overcome this challenge. However, there is an unmet need for imaging modalities...
Published: 6/27/2024   |   Inventor(s): Wojciech Lesniak, Michael Mcmahon, Sridhar Nimmagadda, Nikita Oskolkov, Xiaolei Song, Martin Pomper
Keywords(s): Imaging Agent, Imaging and Sensing Systems, In Vivo Medical Imaging
Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices
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