Search Results - nikita+oskolkov

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Sialicylic Acid -Conjugated Dendrimers as a Tunable, High-Performance CEST MRI NanoPlatform for Diagnostic Imaging

Value Proposition: Brain tumors have poor survival rates and treatment options are limited due to the requirement of therapeutics to cross the blood-brain-barrier to reach the tumor site. Convection-enhanced delivery (CED) of nanoformulations is gaining increasing attention to overcome this challenge. However, there is an unmet need for imaging modalities...

Published: 3/13/2025 | Inventor(s): Wojciech Lesniak, Michael Mcmahon, Sridhar Nimmagadda, Nikita Oskolkov, Xiaolei Song, Martin Pomper

Keywords(s): Imaging Agent, Imaging and Sensing Systems, In Vivo Medical Imaging

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices

A Surface Conjugation Approach to Formulate Nano-carriers for Magnetic Resonance Imaging (MRI) Tracking

Nanoparticle Diagnostic and Therapeutic ImagingJHU REF: [C12327]Invention novelty: Improved method for magnetic resonance imaging of diagnostic and therapeutic nano-carriers.Value PropositionThere is an urgent need to develop simple and safe approaches to image nano-carriers in vivo over the course of treatment, which allows physicians to monitor the...

Published: 3/13/2025 | Inventor(s): Justin Hanes, Himatkumar Patel, Michael Mcmahon, Kannie Chan, Nikita Oskolkov, Tao Yu

Keywords(s): Cancers, Disease Indication, Drug Delivery Vehicle, Imaging Agent, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Magnetic Resonance Imaging (MRI), Nanoparticles, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Medical Devices, Technology Classifications > Therapeutic Modalities

Novel Peptide Hydrogels Generating Chemical Exchange Saturation Transfer MRI Contrast and Uses Thereof

C12189: Novel Self-Assembling Peptide Hydrogels for MRINovelty: Self-assembling peptide hydrogels that can function as non-metallic MRI contrast agents.Value Proposition: Currently used metallic or non-metallic MRI contrast agents have some limitations for in vivo imaging such as toxicity or difficulties in distinguishing the contrast from other sources...

Published: 3/13/2025 | Inventor(s): Nikita Oskolkov, Xiaolei Song, Michael Giano, Joel Schneider, Kannie Chan, Michael Mcmahon

Keywords(s): Drug Delivery Vehicle, Hydrogel, Imaging Agent, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Magnetic Resonance Imaging (MRI), Therapeutic Matter, Therapeutics

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Medical Devices, Technology Classifications > Therapeutic Modalities