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A Surface Conjugation Approach to Formulate Nano-carriers for Magnetic Resonance Imaging (MRI) Tracking

Nanoparticle Diagnostic and Therapeutic ImagingJHU REF: [C12327]Invention novelty: Improved method for magnetic resonance imaging of diagnostic and therapeutic nano-carriers.Value PropositionThere is an urgent need to develop simple and safe approaches to image nano-carriers in vivo over the course of treatment, which allows physicians to monitor the...

Published: 3/13/2025 | Inventor(s): Justin Hanes, Himatkumar Patel, Michael Mcmahon, Kannie Chan, Nikita Oskolkov, Tao Yu

Keywords(s): Cancers, Disease Indication, Drug Delivery Vehicle, Imaging Agent, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Magnetic Resonance Imaging (MRI), Nanoparticles, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Medical Devices, Technology Classifications > Therapeutic Modalities

Novel Peptide Hydrogels Generating Chemical Exchange Saturation Transfer MRI Contrast and Uses Thereof

C12189: Novel Self-Assembling Peptide Hydrogels for MRINovelty: Self-assembling peptide hydrogels that can function as non-metallic MRI contrast agents.Value Proposition: Currently used metallic or non-metallic MRI contrast agents have some limitations for in vivo imaging such as toxicity or difficulties in distinguishing the contrast from other sources...

Published: 3/13/2025 | Inventor(s): Nikita Oskolkov, Xiaolei Song, Michael Giano, Joel Schneider, Kannie Chan, Michael Mcmahon

Keywords(s): Drug Delivery Vehicle, Hydrogel, Imaging Agent, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Magnetic Resonance Imaging (MRI), Therapeutic Matter, Therapeutics

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Medical Devices, Technology Classifications > Therapeutic Modalities

Use of Non-labeled Infusion of Natural Sugars and Detection by MRI for Assessing Tissue Perfusion and Metabolism

C11306: Use of Non-labeled Sugars in MRIValue Proposition: ADVANTAGES:• Provides an alternative approach to measure MR contrast sensitive to both metabolic and vascular properties (perfusion and permeability) of tissue. • Uses a natural biodegradable compound that is already available in the clinic, without the need for paramagnetic, magnetic,...

Published: 3/13/2025 | Inventor(s): Guanshu Liu, Dmitri Artemov, Yoshinori Kato, Kannie Chan, Michael Mcmahon, Peter van Zijl

Keywords(s): Disease Indication, Imaging Agent, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Magnetic Resonance Imaging (MRI), Wound Healing

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Wound Healing, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices