Search Results - fengyi+wan

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A novel mouse strain to screen and validate therapeutics for preventing and treating life-threatening diarrhea

Value PropositionFirst infantile diarrhea model to capture host immune responses to enteric bacterial infections.Exhibits symptoms for lethal and severe infantile enteropathogenic E. coli infection episodes.Allows for discovery and screening of novel drug targets for E. coli infection-associated lethal diarrhea in infantsUnmet NeedThe WHO Global Burden...

Published: 3/14/2025 | Inventor(s): Fengyi Wan

Keywords(s):

Category(s): Clinical and Disease Specializations > Gastroenterology, Technology Classifications > Research Tools > Animal Models

A Rabbit Polyclonal Antibodies Specific for S113 and S117 Phosphorylated Sam68 (Src-associated substrate in mitosis of 68 kDa), an RNA-binding Protein with Multi-functions in the Cell

Value PropositionBinds a potential novel target for pharmacological interventions, as monoclonal antibodies against CD25 are a significant treatment for C25 expressed cancers.Reports phosphorylation of S113 and S117 residues in Sam68, which is critical for the NF-kB-mediated selective transcription of the CD25 gene.Unmet NeedAnnually, there are approximately...

Published: 3/13/2025 | Inventor(s): Fengyi Wan

Keywords(s): Antibodies, Basic Research Biomarker, Discovery/Research Tools, Proteomics/Immunoassays, Proteomics/Immunoassays Antibodies, Research Reagent

Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools