Search Results - gopal+thinakaran

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Mouse neuroblastoma cell lines stably expressing mutated APP as models to study Alzheimer's disease

INVENTION NOVELTY: Researchers have generated transgenic mouse N2a neuroblastoma cells that stably express wild-type or mutated APP, respectively. C-terminally myc-tagged wild-type APP, or APP carrying the Swedish familial Alzheimer's disease (FAD)-specific amino acid substitution were cloned in plasmid pCB6 under control of CMV promoter. Next,...

Published: 7/24/2026 | Inventor(s): Sangram Sisodia, Gopal Thinakaran

Keywords(s): Cancers, Cell Lines, Discovery/Research Tools, Disease Indication, Human Cell Lines, In Vitro Research Tool, Mouse Cell Lines

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Research Tools